Background: Recently, a torque-measuring micromotor has been shown to provide a reliable, quantitative intraoperative evaluation of bone density and implant primary stability. This may be particularly useful for determining bone quality of residual bone and consequently the most appropriate site preparation in the posterior maxilla, where bone often is of low density and quality.
Purpose: This work aimed to assess the medium-term success of implants placed during 1-stage sinus augmentations using an undersized drilling protocol. In case of low bone density, the relationship between residual bone height (RBH) and primary stability was also investigated.
Materials And Methods: Clinical records of patients who underwent sinus augmentation and concomitant implant placement following a 12.5% undersized drilling protocol were retrospectively analyzed. In all patients, bone density measured intraoperatively was ≤ 0.45 g/cm . A minimum of 60 months of follow-up was required for inclusion.
Results: Records of 106 patients who received 253 implants were reviewed. No significant difference in the implant success rate was found for patients who had less than 4 mm of RBH and those who had more.
Conclusions: Underpreparation of the implant-placement sites enabled achievement of successful implant-supported rehabilitation of the posterior maxilla even when both RBH and bone density were low.
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http://dx.doi.org/10.1111/cid.12558 | DOI Listing |
Cardiovasc Diabetol
January 2025
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, No.2 Anzhen Road, Chaoyang District, 100029, Beijing, China.
Introduction: Bone marrow-derived mesenchymal stem cell-derived extracellular vesicles (BMSC-EVs) are widely used for therapeutic purposes in preclinical studies. However, their utility in treating diabetes-associated atherosclerosis remains largely unexplored. Here, we aimed to characterize BMSC-EV-mediated regulation of autophagy and macrophage polarization.
View Article and Find Full Text PDFCalcif Tissue Int
January 2025
University of Pittsburgh, 3860 S. Water St., Pittsburgh, PA, 15203, USA.
Sport participation affects body composition and bone health, but the association between sport, body composition, and bone health in female athletes is complex. We compared areal bone mineral density (aBMD, DXA) and tibial volumetric bone mineral density (vBMD), geometry, microarchitecture, and estimated strength (HR-pQCT) in cross-country runners (n = 22), gymnasts (n = 23) and lacrosse players (n = 35), and investigated associations of total body lean mass (TBLM), team, and their interaction with tibial bone outcomes. Total body (TB), total hip (TH), femoral neck (FN), and lumbar spine (LS) aBMD were higher in gymnasts than runners (p < 0.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Bone Joint, Binzhou Medical University Hospital, No. 661 Huanghe 2nd Road, Binzhou, 256600, China.
This study examines the biocompatibility, osteogenic potential, and effectiveness of polyether ether ketone (PEEK) composites for treating osteonecrosis, seeking to establish a theoretical basis for clinical application. A range of PEEK composite materials, including sulfonated polyether ether ketone (SPEEK), polydopamine-sulfonated polyether ether ketone (SPEEK-PDA), bone-forming peptide-poly-dopamine-sulfonated polyether ether ketone (SPEEK-PDA-BFP), and vascular endothelial growth factor-poly-dopamine-sulfonated polyether ether ketone (SPEEK-PDA-VEGF), were constructed by concentrated sulfuric acid sulfonation, polydopamine modification and grafting of bioactive factors. The experiments involved adult male New Zealand rabbits aged 24-28 weeks and weighing 2.
View Article and Find Full Text PDFJ Biomech
January 2025
Radboudumc, Orthopaedic Research Lab, PO Box 9101, 6500 HB Nijmegen, the Netherlands.
Aseptic loosening is the primary cause of revision in cementless total knee arthroplasty (TKA), emphasizing the importance of strong initial stability for long-term implant success. Pre-clinical evaluations are crucial for understanding implant fixation mechanics and improving implant designs. Finite element (FE) analysis models often use linear elastic bone material models, which do not accurately reflect bone's mechanical behavior.
View Article and Find Full Text PDFJ Bone Joint Surg Am
January 2025
Shriners Children's Northern California, Sacramento, California.
Background: Magnetic resonance imaging (MRI) has not been routinely used for infants with brachial plexus birth injury (BPBI); instead, the decision to operate is based on the trajectory of clinical recovery by 6 months of age. The aim of this study was to develop an MRI protocol that can be performed without sedation or contrast in order to identify infants who would benefit from surgery at an earlier age than the age at which that decision could be made clinically.
Methods: This prospective multicenter NAPTIME (Non-Anesthetized Plexus Technique for Infant MRI Evaluation) study included infants aged 28 to 120 days with BPBI from 3 tertiary care centers.
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