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Aptamer-modified selenium nanoparticles for dark-field microscopy imaging of nucleolin. | LitMetric
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Aptamer-modified selenium nanoparticles for dark-field microscopy imaging of nucleolin.

Meng Li Liu Hong Yan Zou Chun Mei Li Rong Sheng Li Cheng Zhi Huang

Chem Commun (Camb)

Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.

Published: December 2017

Selenium nanoparticles (SeNPs) with strong green scattering light serving as light scattering nanoprobes for dark-field microscopy imaging are developed for the first time. The SeNPs show good stability, excellent biocompatibility, and high light-producing power, and can precisely and specifically target cancer cells with overexpressed nucleolin (NCL) after modification with aptamers, revealing that the SeNPs can act as a good light scattering nanoprobe for bioimaging and biolabeling.

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 Source
http://dx.doi.org/10.1039/c7cc07664aDOI Listing

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