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: a new and emerging pathogen linked to keratomycosis. | LitMetric

: a new and emerging pathogen linked to keratomycosis.

Digit J Ophthalmol

Cornea and External Disease Service, Department of Ophthalmology, Ohio State University College of Medicine, Columbus, Ohio.

Published: December 2017

We describe our experience managing a case of fungal keratitis in a 71-year-old immunocompetent woman. Intracameral cultures isolated , a dimorphic commensal microbe with limited pathogenicity, in an immune competent patient. Repeated corneal cultures for bacteria and fungus were negative. Initial broad-spectrum topical fortified antibiotics were eventually escalated to include topical natamycin and voriconazole and oral voriconazole. The patient underwent emergent corneal transplantation, but recurrent infection eventually required anterior chamber washout and intracameral injection of amphotericin B. A combination of topical, systemic, intracameral administration of voriconazole, intracameral administration of amphotericin B, anterior chamber washout, and penetrating keratoplasty were required to clear the infection.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683434PMC
http://dx.doi.org/10.5693/djo.02.2017.04.001DOI Listing

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