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Air-oxidation from sulfur to sulfone-bridged Schiff-base macrocyclic complexes showing enhanced antimicrobial activities. | LitMetric

Air-oxidation from sulfur to sulfone-bridged Schiff-base macrocyclic complexes showing enhanced antimicrobial activities.

Sci Rep

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Science, Nanjing University, Nanjing, 210093, P. R. China.

Published: November 2017

Two embedded sulfur atoms in a novel [2 + 2] Schiff-base macrocyclic dinuclear Zn(II) complex were found to be easily autoxidized to the sulfone units on air exposure, and the resultant sulfone-functionalized macrocyclic complex was obtained by the post-modification strategy exhibiting enhanced antimicrobial activities because of the presence of dual active sites in comparison with the sulfur-containing Schiff-base macrocycle.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698483PMC
http://dx.doi.org/10.1038/s41598-017-15898-1DOI Listing

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