AI Article Synopsis
- The study focused on determining the seroprevalence of various Leptospira strains in cattle from Uganda, specifically in Kole and Mbale districts.
- A total of 275 bovine serum samples from 130 smallholder farms were tested, revealing an overall seroprevalence of 19.27%, with the highest rates for the Pomona strain.
- Results indicate past exposure to leptospires in the cattle population, with no significant differences observed based on district or gender.
Article Abstract
Seroprevalence of spp. in cattle is unknown in Uganda. The aim of this study was to estimate the seroprevalence of Icterohaemorrhagiae, Pomona, Butembo, Grippotyphosa, Nigeria, Hardjo, Wolfii, and Kenya and an overall seroprevalence in cattle from Kole and Mbale districts. Two hundred-seventy five bovine sera from 130 small holder farms from Kole ( = 159) and Mbale ( = 116), collected between January and July 2015, were tested for antibodies against eight strains by Microscopic Agglutination Test. A titer of ≥100 was considered seropositive, indicating past exposure. Overall, the seroprevalence was 19.27% (95% CI 14.9-24.5%). Pomona seroprevalence was highest with 9.45% (6.4-13.7%), followed by Kenya 5.09% (2.9-8.6%), Nigeria 4.00% (2.1-7.2%), Wolfii 3.27% (1.6-6.3%), Butembo 1.86% (0.7-4.4%), Hardjo 1.45% (0.5-3.9%), and Icterohaemorragiae and Grippotyphosa with less than 1% positive. Seroprevalence did not differ between districts and gender ( ≥ 0.05). Seven animals had titers ≥400. Cross-reactions or exposure to ≥1 serovar was measured in 43% of serum samples. Seroprevalence of 19% implies exposure of cattle to leptospires.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708060 | PMC |
| http://dx.doi.org/10.3390/ijerph14111421 | DOI Listing |
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