Prevalence and antibiogram of methicillin resistant Staphylococcus aureus isolated from medical device-related infections; a retrospective study in Lahore, Pakistan.

Rev Soc Bras Med Trop

Department of Microbiology and Molecular Genetics, University of the Punjab, Quaid-e-Azam Campus, Lahore-54590, Pakistan.

Published: December 2017

AI Article Synopsis

  • Medical devices are increasingly being used in treatments, which can lead to infections.
  • Urinary catheter infections are the most common, followed by central venous catheters and orthopedic implants, with MRSA and E. coli being significant culprits.
  • Antibiotic resistance is a concern, with high resistance rates to ofloxacin and ciprofloxacin, but MRSA remains susceptible to vancomycin.

Article Abstract

Introduction: With the advancement of medicine and surgery, various types of medical devices have become part of treatment strategies.

Methods: Identification and antimicrobial sensitivity testing were done according to CLSI guidelines following standard microbiological practices.

Results: Urinary catheter infections (31%) were most frequent followed by central venous catheter (18%) and orthopedic implants (15%). Methicillin resistant Staphylococcus aureus (MRSA) was a major cause of device-related infection after Escherichia coli (21%); other pathogens were Klebsiella pneumoniae (14%), Pseudomonas spp. (10%), Acinetobacter spp. (8%) and Candida species (7%). None of MRSA was resistant to vancomycin (MIC ≥16µg/mL). Resistance rates were 98% and 97% for ofloxacin and ciprofloxacin, respectively.

Conclusions: Escherichia coli and MRSA are major pathogens of medical device-related infections.

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Source
http://dx.doi.org/10.1590/0037-8682-0352-2016DOI Listing

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