Metabolic bone disease of prematurity.

J Clin Transl Endocrinol

Division of Neonatology, The Children's Hospital of Philadelphia-Pennsylvania Hospital, 800 Spruce Street, Philadelphia, PA 19107, USA.

Published: September 2014

Metabolic bone disease (MBD) of prematurity remains a significant problem for preterm, chronically ill neonates. The definition and recommendations for screening and treatment of MBD vary in the literature. A recent American Academy of Pediatrics Consensus Statement may help close the gap in institutional variation, but evidence based practice guidelines remain obscure due to lack of normative data and clinical trials for preterm infants. This review highlights mineral homeostasis physiology, current recommendations in screening and monitoring, prevention and treatment strategies, and an added perspective of a bone health team serving a high volume referral neonatal intensive care center.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684970PMC
http://dx.doi.org/10.1016/j.jcte.2014.06.004DOI Listing

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