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http://dx.doi.org/10.1016/j.annemergmed.2017.08.002 | DOI Listing |
Toxins (Basel)
December 2024
Poison Control Center, The University of Arizona College of Pharmacy, Tucson, AZ 85724, USA.
The onset, progression, and severity of pain following rattlesnake envenomation are highly variable between patients. Pain can be severe and persistent, seemingly refractory to opioid analgesics. The ability of antivenom to directly relieve pain has not been well studied.
View Article and Find Full Text PDFCutis
October 2024
Department of Orthopaedic Surgery, University of Illinois Chicago.
Pediatr Emerg Care
January 2025
Division of Clinical Toxicology, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
Introduction: Scorpion envenomation is a leading cause of envenomation in our region. Antivenom has been used successfully to treat the systemic manifestations of envenomations inflicted by toxic scorpions. Toxic scorpions common in our area include Leiurus quinquestriatus , Androctonus australis , and Buthus occitanus .
View Article and Find Full Text PDFArch Razi Inst
April 2024
Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.
Since around 100 years ago, the best treatment for millions of global snakebite victims has been polyclonal antivenoms. However, common antivenoms need continuous improvement to reduce rare, their side effects and get better performance. In the present study, Fab antivenom was produced through papain digestion of anti-cobra venom plasma, multi-step purification, and optimization, including ammonium sulfate precipitation and DEAE-cellulose column chromatography.
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