Two new saponins from the leaves of Panax notoginseng.

J Asian Nat Prod Res

a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050 , China.

Published: April 2018

Two new saponins, notoginsenosides Ng1 (1) and Ng2 (2), together with seven known compounds (3-9), were isolated from the leaves of Panax notoginseng. Their structures were elucidated by UV, IR, HRESIMS, and NMR experiments. Compounds 6 and 7 showed moderate cytotoxic activities against HCT-116, with IC values of 4.98 and 0.64 μmol/L, respectively.

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http://dx.doi.org/10.1080/10286020.2017.1403421DOI Listing

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