AI Article Synopsis
- The study investigates the roles of key genes (GHSR1a, GH, GHR, NCAPG, SCD) in growth and lipid metabolism traits in Japanese Black cattle.
- Research involved analyzing 650 steers and 116 heifers for carcass traits, and 158 steers for fatty acid composition traits, revealing significant single and epistatic gene effects.
- Findings suggest that a specific TG-repeat polymorphism in the GHSR1a gene is crucial for interactions affecting fatty acid composition in the cattle's adipose tissue.
Article Abstract
Growth hormone secretagogue receptor 1a (GHSR1a), growth hormone (GH), growth hormone receptor (GHR), non-SMC condensin I complex, subunit G (NCAPG) and stearoyl-CoA desaturase (SCD), are known to play important roles in growth and lipid metabolisms. Single and epistatic effects of the five genes on carcass, price-related and fatty acid (FA) composition traits were analyzed in a commercial Japanese Black cattle population of Ibaraki Prefecture. A total of 650 steers and 116 heifers for carcass and price-related traits, and 158 steers for FA composition traits were used in this study. Epistatic effects between pairs of the five genes were found in several traits. Alleles showing strain-specific differences in the five genes had significant single and epistatic effects in some traits. The data suggest that a TG-repeat polymorphism of the GHSR1a.5'UTR-(TG) locus plays a central role in gene-gene epistatic interaction of FA composition traits in the adipose tissue of Japanese Black cattle.
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| http://dx.doi.org/10.1111/asj.12947 | DOI Listing |
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