Automatic segmentation of tumors in B-Mode breast ultrasound images using information gain based neutrosophic clustering.

Background: Since breast ultrasound images are of low contrast, contain inherent noise and shadowing effect due to its imaging process, segmentation of breast tumors depicting ultrasound image is a challenging task. Thus, a robust breast ultrasound image segmentation technique is inevitable.

Objective: To develop an automatic lesion segmentation technique for breast ultrasound images.

Methods: First, the technique automatically detects the suspicious tumor region of interest and discards the unwanted complex background regions. Next, based on the concept of information gain, the technique applies an existing neutrosophic clustering method to the detected region to segment the desired tumor area. The proposed technique computes information gain values from the local neighbourhood of each pixel, which is further used to update the membership values and the cluster centers for the neutrosophic clustering process. Integrating the concept of entropy and neutrosophic logic features into the technique enabled to generate better segmentation results.

Results: Results of proposed method were compared both qualitatively and quantitatively with fuzzy c-means, neutrosophic c-means and neutrosophic ℓ-means clustering methods. It was observed that the proposed method outperformed the other three methods and yielded the best Mean (TP: 94.72, FP: 5.85, SI: 93.75, HD: 8.2, AMED: 2.4) and Standard deviation (TP: 3.2, FP: 3.7, SI: 3.8, HD: 2.6, AMED: 1.3) values for different quality metrics on the current set of breast ultrasound images.

Conclusion: Study demonstrated that the proposed technique is robust to the shadowing effect and produces more accurate segmentation of the tumor region, which is very similar to that visually segmented by Radiologist.