Metabolic Biomarkers in Heart Failure.

Heart Fail Clin

Department of Cardiovascular Medicine, Heart & Vascular Institute, Cleveland Clinic, Cleveland, OH 44106, USA; Department of Cardiovascular Medicine, Center for Clinical Genomics, Cleveland Clinic, Cleveland, OH 44106, USA. Electronic address:

Published: January 2018

Metabolomics is the study of small, organic molecules within biochemical pathways. With advancement of technology, nuclear magnetic resonance, gas chromatography, and mass spectrometry have allowed for the discovery and analysis of large databases of metabolites implicated in heart failure. Metabolomics also explores the patient and environment interactions and unlocks the link between environmental exposures and the development of cardiovascular disease. Although a relatively new field, metabolomics is poised to become a clinically impactful field that develops novel biomarkers and explores new therapeutic interventions in heart failure.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708887PMC
http://dx.doi.org/10.1016/j.hfc.2017.08.011DOI Listing

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