We examine the effect of physiological cations Na, K, Mg, and Ca on the mechanical properties of bundles of λ-phage DNA using silicon nanotweezers (SNTs). Integrating SNTs with a microfluidic device allows us to perform titration experiments while measuring the effect in real-time. The results show that only for Mg and in particular, at the intra-nuclear concentration (100 mM), the interaction occurs.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659861 | PMC |
| http://dx.doi.org/10.1063/1.5008622 | DOI Listing |
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