The clinical presentations of oral malignancy are diverse. This short article discusses a case of a late-presenting oral malignancy and signifies the importance of general dental and medical practitioners’ knowledge in the diagnosis of oral malignancy. Clinical relevance: Oral malignancy is a life-threatening diagnosis. The importance of a structured systematic approach in the diagnosis is discussed.
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http://dx.doi.org/10.12968/denu.2016.43.4.335 | DOI Listing |
Infect Agent Cancer
January 2025
Shahid Beheshti University of Medical Sciences, Hamadan University of Medical Sciences, Hamadan, Iran.
Both women and men are now confronted with the grave threat of cancers caused by the human papillomavirus (HPV). It is estimated that 80% of women may encounter HPV over their lives. In the preponderance of cases involving anal, head and neck, oral, oropharyngeal, penile, vaginal, vulvar, and cervical malignancies, high-risk HPV (HR-HPV) is the causative agent.
View Article and Find Full Text PDFSupport Care Cancer
January 2025
Department of Preventive and Social Dentistry, Faculty of Dentistry, Federal University of Rio Grande Do Sul, Porto Alegre, Rio Grande Do Sul, Brazil.
Purpose: Radiotherapy (RT) in the head and neck (HN) area causes a series of oral complications and the oral microbiota may play an important role in these complications. The aim of this systematic review was to explore alterations in the oral microbiota among individuals undergoing RT in the HN region.
Methods: A comprehensive search across six databases and grey literature was made.
J Cancer Res Clin Oncol
January 2025
Department of General Dentistry II, Peking University School and Hospital of Stomatology, Beijing, People's Republic of China.
Purpose: This epidemiological study leverages data from the Global Burden of Disease (GBD) database spanning from 1990 to 2021 to analyze the global burden of oral cancer. The research aims to provide a comprehensive assessment of the age-standardized incidence rate (ASIR), age-standardized mortality rate (ASDR), and disability-adjusted life years (DALYs) for oral cancer, examining trends over three decades.
Methods: The study used age standardized rate (ASRs) as an indicator of oral cancer epidemiological data.
Sci Rep
January 2025
Department of Pediatric Oncology/Hematology, University Children's Hospital Basel, University of Basel, Basel, Switzerland.
Salivary cytokines have the potential to serve as biomarkers for evaluating cancer progression and treatment response in specific cancer types. This study explored salivary cytokine profiles in pediatric cancer patients and healthy controls, examining changes during chemotherapy. We conducted a prospective study involving newly diagnosed cancer patients and healthy controls under 19 years old.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea.
There is limited data on the risk of second primary malignancies (SPMs) in Asian melanoma survivors. This study aimed to identify the risk of SPMs in Asian melanoma survivors. Standardized incidence ratios (SIRs) were calculated for overall and specific SPMs.
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