AI Article Synopsis

  • The study analyzes the use of supraclavicular flap (SCF) repair in 30 patients with various head and neck defects, confirming its effectiveness and reliability.
  • The authors compare their findings with literature from 2012 to 2017, highlighting that SCF is suitable for diverse defects and remains reliable in previously treated areas.
  • Their observed complication rates were lower than the average reported in other studies, suggesting SCF as a strong reconstructive option for challenging patients.

Article Abstract

Background: Supraclavicular flap (SCF) repair is widely reported in head and neck surgery in select patients and defects. The authors' objective is to present our series of 30 patients who underwent SCF repair for varying defects and to review the scope and outcome of SCF repair in the literature.

Methods: The authors contributed primary evidence of 30 cases of SCF repair. Our outcomes are compared with those reported in the last 5 years' literature; 33 articles published between January 2012 and January 2017 that present original clinical experience of 528 SCFs.

Results: SCF is suitable for a wide variety of oral cavity, pharyngeal, skull base and cutaneous defects. Consistent with our experience, SCF is highly reliable even in previously irradiated or dissected necks, so long as the supraclavicular artery is intact. Our case series shows minor complications in 3/30 (10%) and flap loss in 1/30 (3.3%) cases. The literature reports a similar rate of complete flap failure of 3.4% and a slightly higher average minor complication rate of 24.6%.

Conclusion: We add our experience of 30 cases of SCF repair to the international literature. We experienced a complication rate lower than the reported average, and maintain that the SCF is an excellent reconstructive option in patients with previously irradiated necks or comorbidities that affect microvasculature and anaesthetic resilience.

Download full-text PDF

Source
http://dx.doi.org/10.1111/ans.14263DOI Listing

Publication Analysis

Top Keywords

scf repair
20
supraclavicular flap
8
scf
8
cases scf
8
complication rate
8
repair
6
flap repair
4
repair free
4
flap
4
free flap
4

Similar Publications

Strategies to repair the meniscus have achieved limited success; thus, a cell-based therapy combined with an appropriate biocompatible scaffold could be an interesting alternative to overcome this issue. The aim of this project is to analyze different cell populations and a collagen gel scaffold as a potential source for meniscus tissue engineering applications. Dermal fibroblasts (DFs) and mesenchymal stem cells (MSCs) isolated from adipose tissue (ASCs) or bone marrow (BMSCs) were analyzed.

View Article and Find Full Text PDF

Hypoxia-inducible factor prolyl hydroxylase (PHD) inhibitors have been approved for treating renal anemia yet have failed clinical testing for inflammatory bowel disease because of a lack of efficacy. Here we used a multimodel multimodal generative artificial intelligence platform to design an orally gut-restricted selective PHD1 and PHD2 inhibitor that exhibits favorable safety and pharmacokinetic profiles in preclinical studies. ISM012-042 restores intestinal barrier function and alleviates gut inflammation in multiple experimental colitis models.

View Article and Find Full Text PDF

Human embryonic stem cell-derived immunity-and-matrix-regulatory cells on collagen scaffold effectively treat rat corneal alkali burn.

Exp Eye Res

November 2024

Department of Ophthalmology, Peking University Third Hospital, Beijing, China; Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China. Electronic address:

Article Synopsis
  • Corneal alkali burns (CAB) are serious eye injuries that can cause significant vision loss, with few treatment options available apart from corneal transplants.
  • This study explores the effectiveness of using immunity and matrix-regulatory cells (IMRCs) combined with collagen scaffolds as a new treatment for CAB in rats.
  • Results showed that this novel treatment not only reduced inflammation and promoted tissue healing but also improved corneal clarity and reduced abnormal blood vessel growth in the affected area.
View Article and Find Full Text PDF
Article Synopsis
  • Primary atopic disorders (PAD) are rare genetic conditions caused by specific gene variants that affect skin and immune function, making diagnosis challenging among common allergic disease cases.
  • Identifying PAD requires recognizing clinical red flags like family history and unusual infections, as conventional lab tests are inadequate for definitive diagnosis.
  • Whole-genome sequencing (WGS) enhances diagnostic efficiency and accuracy, but requires careful interpretation and collaboration among specialists to effectively manage PAD cases.
View Article and Find Full Text PDF

Background: Hypercholesterolemia induces cholelithiasis and dysfunction of gallbladder motility. Interstitial cells of Cajal (ICCs) contribute to gallbladder motility. Emodin modulates the contractility of the gallbladder muscle; however, the underlying mechanism is unknown.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!