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Evaluating a Public Health Assessment and Response Framework: SARS-CoV-2 Spread Under the Controlled Distancing Model of Rio Grande do Sul, Brazil.
Health Secur
January 2025
Ricardo Rohweder, MSc, is a PhD Student, Programa de Pós-Graduação em Genética e Biologia Molecular; Lavinia Schuler-Faccini, PhD, is a Professor, Department of Genética and Programa de Pós-Graduação em Genética e Biologia Molecular; and Gonçalo Ferraz, PhD, is a Professor, Programa de Pós-Graduação em Ecologia and Programa de Pós-Graduação em Genética e Biologia Molecular; all at the Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. Lavinia Schuler-Faccini is also a Professor, Medical Genetics Service of Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
In early 2020, to halt the spread of SARS-CoV-2, the state government of Rio Grande do Sul in Brazil established a public health assessment and response framework known as a "controlled distancing model." Using this framework, the government divided the state into 21 regions and evaluated them against a composite index of disease transmission and health service capacity. Regions were assessed using a color-coded scale of flags that was updated on a weekly basis and used to guide the adoption of nonpharmaceutical interventions.
View Article and Find Full Text PDFTranscatheter Approaches to Atrial Functional Mitral Regurgitation: How Far Have We Come?
Catheter Cardiovasc Interv
December 2024
Heart Valve Center, San Raffaele Hospital, Milan, Italy.
Functional mitral regurgitation (MR) is associated with increased cardiovascular morbidity and mortality and over the past decade, the diagnosis of atrial functional mitral regurgitation (aFMR) has been increasingly observed in the elderly, especially in those with atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF). Annular enlargement, perturbations of annular contraction, and atriogenic leaflet tethering distinguish the pathophysiology of aFMR from the one of ventricular origin. However, no consensus provides recommendations regarding the differential diagnosis and the subsequent management of aFMR.
View Article and Find Full Text PDFStochastic simulation to optimize rice breeding at IRRI.
Front Plant Sci
November 2024
CIRAD, UMR AGAP, Cali, Colombia.
Introduction: Genetic improvement in rice increased yield potential and improved varieties for farmers over the last decades. However, the demand for rice is growing while its cultivation faces challenges posed by climate change. To address these challenges, rice breeding programs need to adopt efficient breeding strategies to provide a steady increase in the rate of genetic gain for major traits.
View Article and Find Full Text PDFModified kinematic alignment better restores plantar pressure distribution than mechanical alignment in total knee arthroplasty: a randomized controlled trial.
Sci Rep
November 2024
Shengli Clinical college of Fujian Medical University, No.134 East Street, Fuzhou, Fujian, China.
Kinematic alignment (KA) in the short to medium term clinical outcomes is superior to the mechanical alignment (MA), but whether it will improve patients' postoperative gait is still controversial. Understanding whether and how KA influences postoperative gait mechanics could provide insights into optimizing alignment philosophy to improve functional outcomes. To investigate the impact of KA versus MA in total knee arthroplasty (TKA) on the operated and contralateral native lower limbs by analyzing plantar pressure distribution during walking gait.
View Article and Find Full Text PDFResearch agenda for ending preventable maternal deaths from postpartum haemorrhage: a WHO research prioritisation exercise.
BMJ Glob Health
November 2024
UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Sexual and Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
Introduction: Postpartum haemorrhage (PPH) remains the leading cause of maternal death. Yet there is a lack of clarity around what research is needed to determine what works and how best to deliver proven PPH interventions. This article describes a WHO-led effort to develop a global PPH research agenda for 2023-2030, to reinvigorate research and innovation while avoiding duplication and waste.
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