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Pharmacotherapy of patients with heart failure and atrial fibrillation: let's get the evidence!
Eur Heart J Cardiovasc Pharmacother
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Medical Clinic I, Cardiology and Angiology, Justus-Liebig-University, Giessen.
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The Psychosis Research Unit, Department of Psychology, Greater Manchester Mental Health NHS Foundation Trust, Prestwich, M25 3BL, UK.
Background: Stigma of mental health conditions hinders recovery and well-being. The Honest, Open, Proud (HOP) program shows promise in reducing stigma but there is uncertainty about the feasibility of a randomized trial to evaluate a peer-delivered, individual adaptation of HOP for psychosis (Let's Talk).
Methods: A multi-site, Prospective Randomized Open Blinded Evaluation (PROBE) design, feasibility randomised controlled trial (RCT) comparing the peer-delivered intervention (Let's Talk) to treatment as usual (TAU).
Geographic disparities and determinants of full utilization of the continuum of maternal and newborn healthcare services in rural India.
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Department of Geography, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Background: To further reduce maternal and neonatal mortality, it is essential for mothers and newborns to fully utilize all essential services within the continuum of maternal and newborn care. However, research on maternal and child health services in India has not sufficiently examined geographical disparities in the full utilization of these services and the factors influencing the full utilization, particularly in rural areas. This study aims to address this critical gap.
View Article and Find Full Text PDFEnhancing childhood immunization coverage in Mozambique and Malawi: Study protocol of a mixed methods evaluation of the 'Let's talk about vaccines' multisite community-based participatory project.
PLoS One
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School of Public Health, Faculty of Community and Health Sciences, University of the Western Cape, Cape Town, South Africa.
Background: Full coverage of childhood vaccines is a persistent challenge in low- and middle-income countries, suggesting the presence of specific contextual barriers. The emergence of the COVID-19 pandemic further worsened the situation. The complementary use of community-based participatory research (CBPR) and human-centered design (HCD) approaches has the potential to effectively create tailored interventions for improving public health outcomes.
View Article and Find Full Text PDFLet's focus on the insula in addiction: A refined anatomical exploration of insula in severe alcohol and cocaine use disorders.
Eur Psychiatry
November 2024
Normandie Université, UNICAEN, INSERM, U1237, PhIND "Physiopathology and Imaging of Neurological Disorders", NeuroPresage Team, Cyceron, Caen, France.
Article Synopsis
- The study investigates the changes in gray matter (GM) volume in the insula, a brain region linked to addiction, comparing severe alcohol use disorder (sAUD) and severe cocaine use disorder (sCUD).
- Researchers analyzed 12 subregions of the insula using a sample of 50 sAUD patients, 61 sCUD patients, and 36 healthy controls, finding overall lower insula volume in both disorders, particularly in the anterior long gyrus (ALG).
- The results highlight both shared and distinct patterns of insula volume deficits between sAUD and sCUD, suggesting that while the insula is important in substance use disorders, each disorder may have unique characteristics that could inform treatment approaches.
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