Background: Dermoscopy is a noninvasive diagnostic technique that allows visualization of structures of the superficial dermis not visible with the naked eye.
Hypothesis/objectives: To assess the usefulness and applicability of dermoscopy for evaluation of healthy equine skin.
Animals: Twelve healthy horses from a research herd.
Methods: Five regions (cheek, lateral neck, dorsum, flank and abdomen) were examined with contact dermoscopy using both nonpolarized and polarized light at both 17-fold and 24-fold magnification. These findings were compared to histological features of skin biopsies cut both longitudinally and transversely.
Results: Using a hand-held dermatoscope with nonpolarized light, epidermal ridges were observed. Using polarized light, follicular openings and distinctly separate epidermal openings of sweat gland ducts were observed in some but not all individuals. Similarities were noted between histological and dermoscopic results.
Conclusions: Although not ideal for visualizing many structures in the superficial dermis of healthy equine skin, dermoscopy allowed visualization of epidermal ridges, hair shafts in the infundibular portion of the hair follicles and sweat gland duct openings. Dermoscopy could potentially be useful in the evaluation of diseases affecting the sweat glands, epidermis and hair shaft.
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http://dx.doi.org/10.1111/vde.12511 | DOI Listing |
Equine Vet J
January 2025
University of Liverpool, Leahurst Campus, Neston, UK.
Background: Obesity has been associated with human obstructive sleep apnoea and canine brachycephalic obstructive airway syndrome. The effect of body condition score (BCS) on structures of the oropharynx, nasopharynx and upper airway of the horse has not been investigated.
Objectives: To investigate the effect of BCS on tongue measurements, soft palate angle and basihyoid depth in horses.
Sci Rep
January 2025
College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China.
Tibetan donkeys inhabit the harsh environment of the Qinghai-Tibet Plateau. Research on serum metabolites related to their high-altitude adaptation is limited compared to other livestock. We used liquid chromatography-mass spectrometry (LC-MS) to analyze serum samples from healthy adult donkeys in Shigatse, Changdu, and Dezhou to evaluate the effects of high altitudes on serum metabolites.
View Article and Find Full Text PDFMol Ther
December 2024
Michael Smith Laboratories, University of British Columbia, Vancouver, Canada V6T1Z4; School of Biomedical Engineering, University of British Columbia, Vancouver, Canada V6T1Z4. Electronic address:
Self-amplifying RNA (saRNA) vectors are a next-generation RNA technology that extends the expression of heterologous genes. Clinical trials have shown the dose-sparing capacity of saRNA vectors in a vaccine context compared to conventional messenger RNA. However, saRNA vectors have historically been based on a limited number of alphaviruses, and only the Venezuelan equine encephalitis virus-based saRNA vaccines have been used clinically.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Clinical Science and Public Health, Faculty of Veterinary Science, Mahidol University, Salaya, Puttamonthon, Nakhon Pathom, 73170, Thailand.
Equine melanocytic neoplasm (EMN) represents a form of skin tumor observed predominantly in grey horses aged over 15 years. Despite its prevalence, current therapeutic and preventive strategies for EMN have been subject to limited investigation. This study endeavors to shed light on potential phosphoproteins present in equine serum and fecal samples, potentially linked to EMN, with a specific focus on functional interactions in EMN pathogenesis.
View Article and Find Full Text PDFJ Equine Vet Sci
December 2024
Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, 550 University Ave, Charlottetown Prince Edward Island, Canada C1A 4P3. Electronic address:
Alcohol-based antisepsis has shown experimentally to be as effective as 4 % chlorhexidine gluconate (CHG) at reducing bacterial counts (colony forming units; CFU) on equine skin. Our objectives were to determine the immediate and post-surgical reduction in CFU/mL on equine skin prepared with CHG-based or 70 % isopropyl alcohol (IPA)-based (without CHG) protocols in a clinical setting with arthroscopic surgery. Our hypotheses were that the logCFU/mL reduction would not significantly differ between protocols immediately after preparation or at the end of surgery.
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