Female Wolffian adnexal tumor (WAT) is a rare neoplasm arising from the remnants of the mesonephric duct and <100 cases have been reported globally. The present case report describes a 73-year-old female patient with WAT in the left ovary which, to the best of our knowledge, is the largest benign WAT tumor to be reported. In addition, the present case report reviewed previous studies on the clinical characteristics and therapy for WAT and the surgery methods for female WAT of ovary were summarized. WATs are typically benign; however, a number factors may increase the risk of malignancy.
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http://dx.doi.org/10.3892/ol.2017.6859 | DOI Listing |
Pathology
December 2024
Department of Surgery, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.
Cancer Rep (Hoboken)
December 2024
Department of Gynaecology, Guangdong Women and Children Hospital, Guangzhou, China.
Background: Wolffian adnexal tumor is a rare type of tumor that was first discovered and reported by Karim-inejad in 1973. Wolffian adnexal tumor lacks specific clinical manifestations and its histological morphology is similar to various other tumors, making it highly prone to misdiagnosis. To enhance our understanding of this disease, we hereby report a case of Wolffian adnexal tumor diagnosed and treated in our hospital.
View Article and Find Full Text PDFArch Gynecol Obstet
December 2024
Gynecologic Oncology, IRCCS Istituto Tumori "Giovanni Paolo II", 70124, Bari, Italy.
Front Oncol
September 2024
Department of Obstetrics & Gynecology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Adv Anat Pathol
January 2025
Department of Pathology, Massachusetts General Hospital, Boston, MA.
STK11 adnexal tumor is a novel malignant neoplasm of uncertain histogenesis frequently arising in a para-adnexal location and associated with Peutz-Jeghers syndrome in ∼50% of patients. Its broad morphologic spectrum and nonspecific immunohistochemical profile has resulted in misclassification in the past as a variety of other neoplasms including those of wolffian, sex cord-stromal, mesothelial, and epithelial derivation. This review focuses on the spectrum of adnexal neoplasms that may develop in Peutz-Jeghers syndrome, with particular emphasis on STK11 adnexal tumor and its differential diagnosis.
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