Screening of Norharmane from Seven Cyanobacteria by High-performance Liquid Chromatography.

Pharmacogn Mag

Department of Chemistry, Faculty of Arts and Sciences, Gaziosmanpasa University, Tokat, Turkey.

Published: October 2017

Background: Cyanobacteria, including pharmaceutically and medicinally valuable compounds attract the great attention lately. Norharmane (9H-pyrido (3,4-b) indole found in some cyanobacteria revealed a great number of biological effects.

Objective: Seven cyanobacteria were isolated and identified from Yesilirmak River and Gaziosmanpasa University Campus to determine the norharmane content.

Materials And Methods: Cyanobacteria collected from Tokat, Turkey were isolated and identified by morphologically. Norharmane (9H-pyrido [3,4-b] indole) quantities were presented for seven cyanobacteria, (Kütz.) Nägeli, (Geitler) Anagnostidis, Bornet ex Bornet and Flahault, F. E. Fritsch, Lemmermann, . Kützing ex Gomont, and . Kutzing ex E. Bornet and by high-performance liquid chromatography.

Results: The norharmane amount indicated for cyanobacterial culture media altered in a species-dependent kind in the range of 0.81-10.87 μg/g. produced the most norharmane among the investigated cyanobacteria as 10.87 μg/g.

Conclusion: Cyanobacteria could be an important source of norharmane as well as pharmaceutically valuable compounds.

Summary: Seven cyanobacteria were isolated and identified from Yesilirmak RiverQuantitative analysis of norharmane was executed on isolated cyanobacteriaFour cyanobecteria species included the norharmane contained the most norharmane (10.87 μg/g). HPLC: High performance liquid chromatograph.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669122PMC
http://dx.doi.org/10.4103/pm.pm_214_17DOI Listing

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