Investigating the Role of Global Histogram Equalization Technique for Technetium-Methylene diphosphonate Bone Scan Image Enhancement.

Purpose Of The Study: Technetium-methylene diphosphonate (Tc-MDP) bone scan images have limited number of counts per pixel, and hence, they have inferior image quality compared to X-rays. Theoretically, global histogram equalization (GHE) technique can improve the contrast of a given image though practical benefits of doing so have only limited acceptance. In this study, we have investigated the effect of GHE technique for Tc-MDP-bone scan images.

Materials And Methods: A set of 89 low contrast Tc-MDP whole-body bone scan images were included in this study. These images were acquired with parallel hole collimation on Symbia E gamma camera. The images were then processed with histogram equalization technique. The image quality of input and processed images were reviewed by two nuclear medicine physicians on a 5-point scale where score of 1 is for very poor and 5 is for the best image quality. A statistical test was applied to find the significance of difference between the mean scores assigned to input and processed images.

Results: This technique improves the contrast of the images; however, oversaturation was noticed in the processed images. Student's -test was applied, and a statistically significant difference in the input and processed image quality was found at < 0.001 (with α = 0.05). However, further improvement in image quality is needed as per requirements of nuclear medicine physicians.

Conclusion: GHE techniques can be used on low contrast bone scan images. In some of the cases, a histogram equalization technique in combination with some other postprocessing technique is useful.