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Supervised pulmonary tele-rehabilitation and individualized home-based pulmonary rehabilitation for patients with COPD, unable to participate in center-based programs. The protocol for a multicenter randomized controlled trial - the REPORT study.
PLoS One
January 2025
Respiratory Research Unit and Department of Respiratory Medicine, Copenhagen University Hospital-Hvidovre, Hvidovre, Denmark.
Introduction: Chronic obstructive pulmonary disease (COPD) costs EURO 1.4 billion annually in healthcare costs. Pulmonary rehabilitation (PR) is a vital aspect of care for patients with COPD, but despite the compelling evidence, it is delivered to less than 30%.
View Article and Find Full Text PDFLong-Term Remission Rate of Type 2 Diabetes Following Bariatric Surgery: A Retrospective Cohort Study in Adult Patients in Riyadh, Saudi Arabia.
Cureus
January 2025
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Article Synopsis
- Type 2 Diabetes Mellitus (T2DM) is a prevalent chronic condition in Saudi Arabia, and while bariatric surgery is known to aid in weight loss and potentially induce remission, long-term effects specific to the Saudi population are not well understood.
- A retrospective study analyzed medical records of 74 Saudi adults who underwent bariatric surgery from 2016-2020, focusing on changes in Hemoglobin A1c (HbA1c) levels pre-and post-surgery and evaluating diabetes remission based on American Diabetes Association criteria.
- Results showed significant improvements in glycemic control, with mean HbA1c levels dropping from 8.70 to 6.76 after one year; however, only 27%
Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitors.
J Immunother Cancer
January 2025
Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Background: Immune checkpoint inhibitors (ICIs) are recommended to treat patients with deficient mismatch repair/microsatellite instability high (dMMR/MSI-H) metastatic colorectal cancer (mCRC). Pivotal trials have fixed a maximum ICI duration of 2 years, without a compelling rationale. A shorter treatment duration has the potential to improve patients' quality of life and reduce both toxicity and cost without compromising efficacy.
View Article and Find Full Text PDFINVITED REVIEW: A review of some commonly used meta-analysis methods in dairy science research.
J Dairy Sci
December 2024
Department of Animal Science, Michigan State University, East Lansing, MI, USA, 48824. Electronic address:
Meta-analyses have become increasingly common, providing meaningful summaries of cumulative knowledge in the dairy science literature. Some of the corresponding meta-analytic techniques have been developed by knowledgeable dairy scientists, some of which pre-date tractable likelihood-based random or mixed effects model meta-analytic techniques and associated software developed by statisticians. This review compares various meta-analytic techniques on aggregate data (i.
View Article and Find Full Text PDFFactors associated with the success of restorative treatment for root caries: A systematic review with meta-analysis.
J Dent
December 2024
Faculty of Dentistry, The University of Hong Kong, Hong Kong, China. Electronic address:
Objectives: The aims of this systematic review were to estimate the success rates of root caries restorations, and to identify possible factors associated with the success of root caries restorations.
Data And Sources: Literature search was conducted in three databases, PubMed, MEDLINE and Web of Science to identify clinical studies reporting on the success of restorative treatment for root caries. Factors that may influence clinical outcomes of the restorative treatment were summarized and analyzed.
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