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Successful rituximab treatment in IgG4-related coronary periarteritis: a case-based review.
Rheumatol Int
December 2024
Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated disorder characterized by elevated serum IgG4 levels and the enlargement and fibrosis of organs. As a rare manifestation, coronary arteries can be affected by IgG4-RD as coronary periarteritis, leading to serious complications such as stenosis or aneurysm. Although coronary periarteritis poses a life-threatening condition, optimal treatment strategies remain unclear due to its extreme rarity.
View Article and Find Full Text PDFA case report of porcine circovirus 3 (PCV3) reproductive disease in Iberian semi-outdoor reared sows.
Porcine Health Manag
November 2024
Unitat mixta d'investigació IRTA- UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Catalonia, 08193, Spain.
Article Synopsis
- Porcine circovirus 3 (PCV3) is a newly identified pathogen linked to reproductive issues in pigs, notably in intensive farming setups.
- A case study from a semi-outdoor Iberian sow farm highlighted significant reproductive disease symptoms, including a rise in mummified fetuses and stillborn piglets primarily among gilts, while multiparous sows remained unaffected.
- Investigations confirmed the presence of PCV3 through tissue analysis, displaying specific lesions such as lymphohistiocytic myocarditis, marking the first documented incidence of PCV3 reproductive disease in this farming system.
Coronary Periarteritis in Immunoglubulin G4-Related Disease: Imaging and Regression of Tumour-Like Masses.
Can J Cardiol
January 2025
Division of Cardiology, St Paul's and Vancouver General Hospital, Vancouver, British Columbia, Canada; Centre for Heart Valve Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Presented case study deals with the sudden death of a 47 years old male, shortly after a mountain bike race after reported nausea and chest pain followed by loss of consciousness and resuscitation. Cardiopulmonary resuscitation was unsuccessful. An autopsy was enacted due to the sudden death in a seemingly healthy person.
View Article and Find Full Text PDFCoronary periarteritis and pericarditis are rare but distinct manifestations of heart involvement in IgG4-related disease: a retrospective cohort study.
Orphanet J Rare Dis
July 2024
Department of Rheumatology, Peking Union Medical College Hospital National Clinical Research Center for Dermatologic and Immunologic Diseases Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, China.
Article Synopsis
- The heart can be affected by a disease called IgG4-related disease (IgG4-RD), which is rare but important to study.
- In a study of 42 patients, researchers looked at the heart problems caused by this disease and how well treatments worked.
- Most patients responded well to treatments like glucocorticoids, but some had relapses, showing that careful monitoring is needed even after treatment.
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