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The optimal annual case volume for acute type A aortic dissection surgery in relation to long-term outcomes.
Eur J Cardiothorac Surg
January 2025
Department of Cardiothoracic Surgery, Maastricht University Medical Centre (MUMC+), Netherlands.
Objectives: Previous analyses of the volume-outcome relationship have focused on short-term outcomes such as early mortality. The current study aims to update a novel statistical methodology, facilitating the evaluation of the relation between procedural volume and time-to-event outcomes such as long-term survival, using surgery for acute type A aortic dissection as an illustrative example.
Methods: This study employed an existing dataset of type A dissection outcomes, retrieved from literature.
Neck vessels geometry and diameter change in patients with acute type A aortic dissection.
Gen Thorac Cardiovasc Surg
January 2025
Department of Cardiovascular Surgery, Nerima Hikarigaoka Hospital, 1-5-2, Hikarigaoka, Nerima-ku, Tokyo, Japan.
Objective: Branched prostheses are used to treat aortic arch with dissection. However, changes in the neck vessel geometry and diameter after dissection are not well known. We aimed to evaluate neck vessels geometry and changes in diameter with dissection.
View Article and Find Full Text PDFCurrent Paradigm and Future Directions in the Management of Nodal Disease in Locally Advanced Cervical Cancer.
Cancers (Basel)
January 2025
Department of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China.
Approximately 36% of patients with cervical cancer present with regional nodal metastasis at diagnosis, which is associated with adverse survival outcomes after definitive treatment. In the modern era of chemoradiotherapy (CRT) and image-guided adaptive brachytherapy (IGABT), where excellent local control is achieved for patients with locally advanced cervical cancer (LACC), nodal failure remains a major challenge to cure. To optimize treatment outcomes for node-positive LACC and reduce the incidence of nodal failure, various treatment approaches have been explored, including methods of surgical nodal staging or dissection, RT dose escalation strategies, such as intensity-modulated radiotherapy (IMRT) with simultaneous integrated boost (SIB) to involved nodes, and elective treatment of subclinical para-aortic (PAO) disease.
View Article and Find Full Text PDFA Narrative Review of Biomarkers and Imaging in the Diagnosis of Acute Aortic Syndrome.
Diagnostics (Basel)
January 2025
Department of Cardiovascular Surgery, Faculty of Medicine, Atatürk University, Erzurum 25030, Türkiye.
Acute aortic syndrome (AAS) encompasses a range of life-threatening conditions, including classical dissection, intramural hematoma, and penetrating aortic ulcer. Each of these conditions presents distinct clinical characteristics and carries the potential to progress to rupture. Because AAS can be asymptomatic or present with diverse symptoms, its diagnosis requires clinical evaluation, risk scoring, and biomarkers such as D-dimer (DD), C-reactive protein (CRP), homocysteine, natriuretic peptides (BNP), and imaging modalities like computed tomography (CT), magnetic resonance imaging (MRI), and echocardiography.
View Article and Find Full Text PDFCerebral Oximetry Index-Guided Blood Pressure Management During Cardiopulmonary Bypass Reduces Postoperative Delirium in Patients with Acute Type A Aortic Dissection.
J Cardiothorac Vasc Anesth
January 2025
Department of Anesthesiology, The Yangzhou Clinical Medical College of Xuzhou Medical University, Yangzhou, Jiangsu Province, China. Electronic address:
Objective(s): To investigate whether cerebral oximetry index (COx)-guided blood pressure management during cardiopulmonary bypass (CPB) could reduce postoperative delirium (POD) in patients undergoing acute type A aortic dissection (ATAAD) repair.
Design: A prospective, randomized controlled trial.
Setting: Patients undergoing ATAAD repair with CPB.
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