Automated 3D method for the construction of flexible and reconfigurable numerical breast models from MRI scans.

Med Biol Eng Comput

Department of Electrical and Computer Engineering, Schulich School of Engineering, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada.

Published: June 2018

Anatomically realistic numerical breast models are essential tools for microwave breast imaging, supporting feasibility analysis, performance verification, and design improvements. Patient-specific models also assist in interpreting the results of the patient studies conducted on microwave imaging prototype systems. The proposed method employs automated and robust 3D processing techniques to construct flexible and reconfigurable breast models. These techniques include noise and artifact suppression with a principal component analysis (PCA) approach, and oversampling of the magnetic resonance imaging (MRI) data to enhance the intensity continuity. The k-means clustering segmentation identifies fatty and fibroglandular tissues and further segments these regions into a selected number of tissues, providing reconfigurable models. A peak Gaussian fitting technique maps the model clusters to the dielectric properties. The robustness of the proposed method is verified by applying it to both 1.5- and 3-T MRI scans as well as to scans of varying breast densities.

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http://dx.doi.org/10.1007/s11517-017-1740-9DOI Listing

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