We investigate a specific diversity phase for phase diversity (PD) phase retrieval, which possesses higher accuracy than common PD, especially for large-scale and high-frequency wavefront sensing. The commonly used PD algorithm employs the image intensities of the focused plane and one defocused plane to build the error metric. Unlike the commonly used PD, we explore a bisymmetric defocuses diversity phase, which employs the image intensities of two symmetrical defocused planes to build the error metric. This kind of diversity phase, named PD-BD (bisymmetric defocuses phase diversity), is analysed with the Cramer-Rao lower bound (CRLB). Statistically, PD-BD shows smaller CRLBs than the commonly used PD, which indicates stronger capacity of phase retrieval. Numerical simulations also verify that PD-BD has higher accuracy of phase retrieval than the commonly used PD when dealing with large-scale and high-frequency wavefront aberrations. To further affirm that PD-BD possesses higher accuracy of wavefront sensing than PD, we also perform a simple verification experiment.
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http://dx.doi.org/10.1038/s41598-017-15597-x | DOI Listing |
Rheumatol Adv Pract
January 2025
Rheumatology Unit, ERN ReCONNET Center, IRCCS Meyer Children's Hospital, Firenze, Italy.
Objectives: Two different European Reference Networks cover CTDs with paediatric onset, the European Reference Network on Rare and Complex Connective Tissue Diseases (ERN ReCONNET) and the European Reference Network on Rare Immunological Disorders (ERN RITA). The transition of care is a significant focus, with ReCONNET centres actively addressing this through updated programs. Despite these efforts, challenges persist.
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January 2025
Center for Research in Biological Chemistry and Molecular Materials (CIQUS), Department of Chemical Engineering, Universidade de Santiago de Compostela Rúa de Jenaro de la Fuente, s/n 15705 Santiago de Compostela Spain
For decades, extensive surfactant libraries have been developed to meet the requirements of downstream applications. However, achieving functional diversity has traditionally demanded a vast array of chemical motifs and synthetic pathways. Herein, a new approach for surfactant design based on structural isomerism is utilised to access a wide spectrum of functionalities.
View Article and Find Full Text PDFRSC Adv
January 2025
Department of Physics and Nanotechnology, Faculty of Engineering and Technology, SRM Institute of Science and Technology Kattankulathur Chennai Tamil Nadu 603203 India.
This research aims to develop YCuMnO double perovskite, using a citrate auto combustion method, to be used as a photocatalyst for the degradation of organic dyes and antibiotics. XRD and Raman characterization revealed the synthesis of pure-phase YCuMnO double perovskite. The X-ray photoelectron spectroscopy results show the presence of +4 and +2 oxidation states of Mn and Cu ions.
View Article and Find Full Text PDFFuture Sci OA
December 2025
Janssen Research & Development LLC, Raritan, NJ, USA.
Background: Including racial and ethnic minorities in clinical trials is essential for advancing health equity. Despite progress, trials often do not mirror patient population demographics.
Methods: The National Library of Medicine's Clinical Trials database was queried for phase III trials of lung, colorectal, breast, and prostate cancers.
J Am Chem Soc
January 2025
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P. R. China.
Modular chemical postmodification of peptides is a promising strategy that supports the optimization and innovation of hit peptide therapeutics by enabling rapid derivatization. However, current methods are primarily limited to traditional bio-orthogonal strategies and chemical ligation techniques, which require the preintroduction of non-natural amino acids and impose fixed methods that limit peptide diversity. Here, we developed the Tyrosine-1,2,3-Triazine Ligation (YTL) strategy, which constructs novel linkages (pyridine and pyrimidine) through a "one-pot, two-step" process combining SAr and IEDDA reactions, promoting modular post modification of Tyr-containing peptides.
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