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Development of a computationally-designed polymeric adsorbent specific for mycotoxin patulin. | LitMetric

Development of a computationally-designed polymeric adsorbent specific for mycotoxin patulin.

Analyst

Leicester Biotechnology Group, Department of Chemistry, College of Science and Engineering, University of Leicester, University Road, Leicester, LE1 7RH, UK.

Published: December 2017

AI Article Synopsis

  • Patulin is a toxic compound mainly found in moldy apples, making its monitoring essential for food safety, especially for vulnerable groups like the elderly and children.
  • A new polymeric adsorbent has been developed for efficiently extracting patulin from apple juice, enabling accurate detection through chromatography.
  • This cost-effective polymer, which binds strongly to patulin due to its unique design, can be mass-produced and serves as a model for creating adsorbents for other toxins in various food products.

Article Abstract

Patulin is a toxic compound which is found predominantly in apples affected by mould rot. Since apples and apple-containing products are a popular food for the elderly, children and babies, the monitoring of the toxin is crucial. This paper describes a development of a computationally-designed polymeric adsorbent for the solid-phase extraction of patulin, which provides an effective clean-up of the food samples and allows the detection and accurate quantification of patulin levels present in apple juice using conventional chromatography methods. The developed bespoke polymer demonstrates a quantitative binding towards the patulin present in undiluted apple juice. The polymer is inexpensive and easy to mass-produce. The contributing factors to the function of the adsorbent is a combination of acidic and basic functional monomers producing a zwitterionic complex in the solution that formed stronger binding complexes with the patulin molecule. The protocols described in this paper provide a blueprint for the development of polymeric adsorbents for other toxins or different food matrices.

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Source
http://dx.doi.org/10.1039/c7an01294bDOI Listing

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