Functional and Biochemical Parameters of Erythrocytes during Mexicor Treatment in Posttraumatic Period after Experimental Blood Loss and Combined Traumatic Brain Injury.

Bull Exp Biol Med

Department of Anesthesiology and Reanimatology, Faculty of Continuing Medical Education, Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia.

Published: November 2017

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Article Abstract

Mexicor treatment (8 mg/kg body weight per day) during the posttraumatic period after concomitant traumatic brain injury and acute blood loss in rats increased electrophoretic mobility and concentration of 2,3-diphosphoglycerate, and reduced malondialdehyde content in erythrocytes. These changes improved hemodynamics and oxygen-transporting function of the blood. The most pronounced effects of Mexicor were observed at the early stages of posttraumatic period.

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http://dx.doi.org/10.1007/s10517-017-3918-4DOI Listing

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