Background And Purpose: Prior to thrombectomy for proximal anterior circulation large vessel occlusion (LVO) stroke, recent trials have utilized CT angiography (CTA) for vascular imaging immediately following noncontrast CT (NCCT) for decision-making, but thin-section NCCT with automated maximum intensity projection (MIP) reconstruction also has high accuracy in demonstrating the site of an occluding thrombus. We hypothesized that performing thin-section NCCT with MIP alone prior to thrombectomy improves the time to groin puncture (GP) compared to performing CTA after NCCT.
Materials And Methods: We performed a retrospective cohort study of anterior circulation LVO thrombectomy at our tertiary care academic medical center. All stroke patients evaluated with thin-section NCCT (0.625 mm) with automated MIP reconstructions alone and those who had additional CTA were included. We excluded transfer patients, in-hospital strokes, posterior circulation strokes, and patients that were evaluated with stroke imaging other than NCCT or CTA prior to thrombectomy. The study groups were compared for duration from NCCT to GP and total stroke imaging duration.
Results: From March 2008 through August 2015, 34 thrombectomy patients met the inclusion/exclusion criteria - 13 in the NCCT and 20 in the NCCT+CTA group. The total stroke imaging duration was shorter in the NCCT group than in the NCCT+CTA group (2 min [1-6] vs. 28 min [23-65]; < 0.001). The NCCT-only group had a shorter time from NCCT to GP (68 min [32-99] vs. 104 min [79-128]; = 0.030).
Conclusion: Avoiding advanced imaging for patients with anterior circulation LVO in whom thin-section NCCT with MIPs reveals a hyperdense sign significantly shortens the imaging-to-GP time.
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http://dx.doi.org/10.1159/000464300 | DOI Listing |
AJNR Am J Neuroradiol
June 2023
School of Life Science and Technology (W.Q.), Huazhong University of Science and Technology, Wuhan, Hubei, China
Background And Purpose: Identifying the presence and extent of intracranial thrombi is crucial in selecting patients with acute ischemic stroke for treatment. This article aims to develop an automated approach to quantify thrombus on NCCT and CTA in patients with stroke.
Materials And Methods: A total of 499 patients with large-vessel occlusion from the Safety and Efficacy of Nerinetide in Subjects Undergoing Endovascular Thrombectomy for Stroke (ESCAPE-NA1) trial were included.
Actas Urol Esp (Engl Ed)
November 2022
Health Sciences University, Gaziosmanpaşa Education and Research Hospital, Urology Clinic, Estambul, Turkey.
Introduction: The perioperative and postoperative concern in percutaneous nephrolithotomy (PNL) is bleeding. Disease-related conditions (such as stone size, stone HU, tract number, and diameter) affecting this situation were determined. To determine independent risk factors that may affect the amount of hemorrhage in PNL.
View Article and Find Full Text PDFInterv Neurol
October 2017
Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Background And Purpose: Prior to thrombectomy for proximal anterior circulation large vessel occlusion (LVO) stroke, recent trials have utilized CT angiography (CTA) for vascular imaging immediately following noncontrast CT (NCCT) for decision-making, but thin-section NCCT with automated maximum intensity projection (MIP) reconstruction also has high accuracy in demonstrating the site of an occluding thrombus. We hypothesized that performing thin-section NCCT with MIP alone prior to thrombectomy improves the time to groin puncture (GP) compared to performing CTA after NCCT.
Materials And Methods: We performed a retrospective cohort study of anterior circulation LVO thrombectomy at our tertiary care academic medical center.
AJNR Am J Neuroradiol
September 2017
From the Departments of Radiology (J.B., O.A.B., E.M.M.S., H.A.M., C.B.L.M.M.).
Background And Purpose: Thrombus CT characteristics might be useful for patient selection for intra-arterial treatment. Our objective was to study the association of thrombus CT characteristics with outcome and treatment effect in patients with acute ischemic stroke.
Materials And Methods: We included 199 patients for whom thin-section NCCT and CTA within 30 minutes from each other were available in the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute ischemic stroke in the Netherlands (MR CLEAN) study.
J Neurointerv Surg
July 2013
Department of Radiology, Division of Interventional Neuroradiology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.
Background And Purpose: Recent studies have demonstrated that in acute ischemic stroke patients, thin section non-contrast CT (NCCT) can be used to determine the length of the hyperdense intracranial thrombus, and that clot length using this approach predicts the likelihood of vessel recanalization after intravenous tissue plasminogen activator.
Summary Of Case: An acute ischemic stroke patient presented with a left middle cerebral artery occlusion and underwent emergent catheter based therapy. Clot length was determined using pretreatment thin section NCCT and was independently confirmed by the pathologist after whole clot extraction.
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