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http://dx.doi.org/10.4103/ojo.OJO_222_2015 | DOI Listing |
Ther Adv Ophthalmol
November 2024
Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital, No. 95, Wenchang Road, Shilin District, Taipei City 111,Taiwan.
Congenital aniridia is a rare genetic eye disorder often associated with PAX6 gene mutations, leading to complex ocular manifestations, including aniridia-associated keratopathy (AAK) and cataracts. The surgical management of cataracts in these patients is particularly challenging due to severe corneal opacities, which obscure key surgical steps such as capsulorhexis and phacoemulsification. This report presents two cases of congenital aniridia with severe AAK, in which chandelier retroillumination-assisted cataract surgery was employed.
View Article and Find Full Text PDFVet Med Sci
January 2025
Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Background: Pupillary light reflex (PLR) and menace response are among the tests used in neurological and ophthalmic examinations in animals.
Objective: The intent of this study was to investigate the development of the PLR and menace response in neonatal camel calves.
Methods: Thirty healthy camel calves were studied after birth until the menace response and PLR were well established.
Mol Phylogenet Evol
December 2024
School of Life Sciences, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Pleuromamma (Giesbrecht, 1898) is a cosmopolitan genus of metridinid copepods, with species that perform remarkable diel vertical migrations (DVM) and emit a bioluminescent secretion when disturbed that varies both spectrally and kinetically. Copepod bioluminescence is autogenic and uses luciferase enzymes that catalyze a luciferin, coelenterazine, to produce light. Pleuromamma possess naupliar eyes, relatively simple photosensitive structures used for many visually-guided behaviors.
View Article and Find Full Text PDFAdv Sci (Weinh)
November 2024
Translational Cell Therapy Center, China Medical University Hospital, No. 2, Yude Rd., North Dist., Taichung City, 404, Taiwan.
Immunotherapy targeting immune checkpoints (ICPs), such as programmed death-ligand-1 (PD-L1), is used as a treatment option for advanced or metastatic non-small cell lung cancer (NSCLC). However, overall response rate to anti-PD-L1 treatment is limited due to antigen heterogeneity and the immune-suppressive tumor microenvironment. Human leukocyte antigen-G (HLA-G), an ICP as well as a neoexpressed tumor-associated antigen, is previously demonstrated to be a beneficial target in combination with anti-PD-L1.
View Article and Find Full Text PDFJ Neuroophthalmol
September 2024
Stein Eye Institute (LKG); and Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California; and Stein Eye Institute (PAQ); and Department of Ophthalmology, Doheny Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, California.
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