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Choroidal melanoma: A short review with an Indian perspective. | LitMetric

Choroidal melanoma: A short review with an Indian perspective.

Oman J Ophthalmol

Department of Vitreoretina, Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Published: January 2017

AI Article Synopsis

  • Choroidal melanoma (CM) is the most common eye tumor in adults but remains rare in Asia, requiring early detection due to its high risk of metastasis and poor survival rates.
  • While it has specific clinical characteristics, some lesions may mimic CM, making fine-needle aspiration biopsy useful for diagnosis and prognosis.
  • The article explores CM's epidemiology, clinical features, diagnosis, management approaches including radiation for eye preservation, and shares findings from a 9-year analysis at a tertiary care center in India.

Article Abstract

Choroidal melanoma (CM), the most common intraocular tumor in adults, is still a rarity in Asia. Having a high propensity for metastasis with a poor survival, recognizing it early is essential. Although it has typical clinical features, there are instances of simulating lesions. Fine-needle aspiration biopsy can be a valuable tool not only to confirm our clinical suspicion but also aid in prognosticating it. From days of histopathological prognostic markers, we are moving on to genetic markers which are reliably providing insights, helping us in providing a better care for our patients. Eye preservation has taken an all new important meaning in CM with many centers opting for different modalities of radiation. Herein, we try to provide a short synopsis of CM looking into its epidemiology, clinical features, diagnosis, and management. We also look briefly into the role of fine-needle biopsy in managing CM. Being a tertiary referral ocular center in India, we do come across CM; we have shared the preliminary reports of our analysis of managing CM over a 9-year period.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657153PMC
http://dx.doi.org/10.4103/ojo.OJO_234_2016DOI Listing

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