AI Article Synopsis
- Immune-mediated neuropathies are peripheral nerve disorders caused by inflammation that leads to motor or sensory deficiencies.
- Intravenous immunoglobulin (IVIg) has proven effective in treating the most common types of these neuropathies, including Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy.
- The review discusses the reasons for using IVIg, including its mechanism of action, clinical evidence supporting its effectiveness, and important practical considerations for patients and healthcare providers.
Article Abstract
Immune-mediated neuropathies are a group of peripheral nerve disorders characterized by motor or sensory deficits caused by inflammation leading to demyelination or axonal injury. Intravenous immunoglobulin (IVIg) has been demonstrated to be an effective therapy for the 3 most common immune-mediated neuropathies: Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy. This review summarizes current data on the rationale for the use of IVIg in immune-mediated neuropathies, addressing mechanism of action, clinical evidence, and practical considerations for its use.
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| http://dx.doi.org/10.1097/NAN.0000000000000248 | DOI Listing |
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