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| http://dx.doi.org/10.1016/j.ebiom.2017.10.022 | DOI Listing |
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CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Gif-sur-Yvette, France.
DNA topology is a direct consequence of the double helical nature of DNA and is defined by how the two complementary DNA strands are intertwined. Virtually every reaction involving DNA is influenced by DNA topology or has topological effects. It is therefore of fundamental importance to understand how this phenomenon is controlled in living cells.
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École des Hautes Etudes en Sciences Sociales, Paris, France.
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- Recent US proposals to define Alzheimer's disease solely by β-amyloidosis have sparked significant debates, reminiscent of past discussions about the importance of brain lesions and clinical presentation.
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The SARS-CoV-2 virus, a novel member of the Coronaviridae family, is responsible for the viral infection known as Coronavirus Disease 2019 (COVID-19). In response to the urgent and critical need for rapid detection, diagnosis, analysis, interpretation, and treatment of COVID-19, a wide variety of bioinformatics tools have been developed. Given the virulence of SARS-CoV-2, it is crucial to explore the pathophysiology of the virus.
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