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Gun-Sight Technique With Dual Hepatic Vascular Embolization for Sigmoidal Refractory Biliary Stricture After Living-Donor Liver Transplantation: A Case Report.
Transplant Proc
December 2024
Division of Hepatobiliary and Pancreas Surgery, Department of Surgery, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Background: Biliary stricture is a common complication after living-donor liver transplantation (LDLT), but its management is challenging. We herein report a case of successful internal drainage achieved through combination of the gun-sight technique and dual hepatic vascular embolization (DHVE).
Case Presentation: A 54-year-old woman with primary biliary cholangitis underwent ABO-incompatible LDLT with the right lobe.
Sublingual Administration of Tacrolimus is Safe and Provides Similar Drug Exposure to Per-oral Route in Liver Transplant Recipients During Early Postoperative Period-A Large, Retrospective, Observational Study.
J Clin Exp Hepatol
October 2024
Department of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, BLK MAX Super Specialty Hospital, New Delhi, India.
Background/aims: Per-oral (PO) administration of tacrolimus (TAC) results in inadequate trough levels in the early postoperative period in liver-transplant (LT) recipients who undergo Roux-en-Y hepaticojejunostomy for biliary reconstruction. Sublingual administration (SL) of tacrolimus provides an alternative route in such patients.The objectives of this study were to assess the feasibility and safety of SL tacrolimus in adult LT-recipients in the early postoperative period and to compare therapeutic efficacy of SL administration of tacrolimus versus PO route.
View Article and Find Full Text PDFMatching the opposites: liver transplantation from a situs viscerum inversus totalis donor.
Updates Surg
November 2024
Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University Hospital of Modena "Policlinico", University of Modena and Reggio Emilia, 41124, Modena, Italy.
Situs viscerum inversus totalis (SIT) is a rare congenital anomaly. Deceased donors with this condition are often declined because of the technical issues in both the organ's procurement and its transplant. Only eight cases of deceased donor organs with SIT were reported to be used for liver transplantation (LT).
View Article and Find Full Text PDFRisk factors for biliary strictures and leaks after living-donor liver transplantation: a systematic review and meta-analysis.
J Gastrointest Surg
November 2024
Department of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, United States. Electronic address:
Article Synopsis
- Liver transplantation is essential for treating end-stage liver disease; however, many patients die waiting for organs, leading to the exploration of living-donor liver transplantation (LDLT) despite its complications like biliary stricture and leaks.
- This meta-analysis evaluated multiple studies to identify predictors of biliary complications following LDLT, analyzing over 9,400 patients across 22 studies.
- Key findings revealed a 22% rate of biliary stricture and a 14% rate of biliary leak post-LDLT, with significant predictors for stricture including postoperative bile leak and certain anatomical factors related to liver grafts.
Efficacy of Self-Expandable Absorbable Stents during Liver Transplant to Minimize Early Biliary Complications.
Ann Surg
August 2024
Department of General and Digestive Surgery, Virgen de la Arrixaca University Hospital, IMIB-Arrixaca, Murcia, Spain.
Objective: We analyzed the use of a self-expandable absorbable biliary stent (SEABS) to reduce biliary complications in liver transplant (LT).
Background: Complications related to biliary anastomosis are a still a challenge in LT with a high impact on the patient outcomes and hospital costs.
Methods: This non-randomized prospective study was conducted between July 2019 and September 2023 in adult LT patients with duct-to-duct biliary anastomoses.
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