Chronic gingivostomatitis in dogs is an inflammatory syndrome of the oral cavity, which treatment and control of concomitant periodontitis allow healing in most of the cases. In the presence of recurrent lesions, invasive methods are necessary to treat lesions and pain. As a conservative adjuvant method, photobiomodulation (PBM) with low power laser is able to promote reduction of tissue pain and tissue inflammation besides increasing vascularization and healing, restoring the normal function of the irradiated organ in a shorter time. In veterinary medicine, there is no standardization of technique for its use in oral tissue for treating gingivostomatitis in dogs. In the present case, a dog was submitted to aPDT (7.2J/point, 3min/point, 180J/cm) and PBM (1.6J/point, 40s/point, 25J/cm), using a semiconductor diode laser, with wavelength of 660nm, spot size of 0.04cm and output power of 40mW. The established protocol proved to be effective as coadjutant treatment for chronic gingivostomatitis, restoring the integrity of dog's affected mucosa and gingiva.
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http://dx.doi.org/10.1016/j.pdpdt.2017.10.012 | DOI Listing |
S D Med
September 2024
Avera Medical Group Infectious Disease Specialists, Sioux Falls, South Dakota.
Eczema herpeticum (EH) is a potentially life-threatening condition, especially in the pediatric population, that occurs among patients with atopic dermatitis (AD). AD is a chronic inflammatory skin disorder with a complex pathophysiology that predisposes patients to EH. Herpes simplex virus (HSV) 1 is implicated in 90 % of EH cases and often initially presents with gingivostomatitis.
View Article and Find Full Text PDFJ Vet Intern Med
December 2024
Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Background: Chronic gingivostomatitis in cats (FCGS) is a moderately to severely painful condition, potentially caused by inadequate immune response to oral antigenic stimulation. Salivary peptidome analysis can identify inflammatory protein mediators and pathways involved in oral mucosal immune activation and may indicate potential therapeutic options for FCGS.
Objective: Evaluate the diversity and abundance of salivary peptides in cats with FCGS using matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF MS) and nanoscale liquid chromatography-tandem mass spectrometry (nano LC-MS/MS).
Photodiagnosis Photodyn Ther
December 2024
Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Biochemistry & Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Center of Applied Nanomedicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:
Feline chronic gingivostomatitis (FCGS) is a painful and severe inflammatory mucosal disease in cats that presents significant challenges in treatment. This case study describes a novel approach for a cat with FCGS that was unresponsive to antibiotics, non-steroidal anti-inflammatory drugs, and dental extraction. The cat exhibited rapid improvement after undergoing oral indocyanine green (ICG)-mediated antimicrobial photodynamic therapy (aPDT); however, treatment was discontinued due to an episode of anaphylaxis.
View Article and Find Full Text PDFAnimals (Basel)
September 2024
NutricareVet, São Paulo 05690-080, Brazil.
Feline stomatitis or gingivostomatitis is a chronic inflammatory condition affecting approximately 0.7% of patients. The cause is multifactorial, involving infectious agents, genetic factors, and environmental influences.
View Article and Find Full Text PDFObjective: Comparing the utility of the anti-human serum amyloid A (SAA)-specific monoclonal and polyclonal antibodies assays (LZ-SAA) with the pure monoclonal anti-human antibody assays (VET-SAA) during clinical practice in primary care hospital populations by measuring SAA measurement in healthy and diseased domestic cats.
Animals: 52 healthy and 185 diseased client-owned cats.
Methods: SAA concentration was measured using different LZ-SAA and VET-SAA measurements for healthy and various diseased cats.
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