AI Article Synopsis
- The study focuses on the high prevalence of Methicillin-resistant Staphylococcus aureus (MRSA) infections in burn patients in Iran, highlighting its significance in causing infections and mortality.
- A systematic review and meta-analysis of 555 articles yielded 13 relevant studies, revealing that 77.9% of culture-positive burn patients were infected with MRSA.
- The findings suggest an urgent need for improved infection control measures, including hand hygiene, education on antibiotic use, and environmental cleaning to effectively manage MRSA in burn units.
Article Abstract
Objectives: Methicillin-resistant Staphylococcus aureus (MRSA) is considered a major cause of infection and mortality in burn patients, especially when nosocomially acquired. However, limited information is available on the prevalence of MRSA among burn patients in Iran.
Methods: A systematic search was performed using different electronic databases including Medline (via PubMed), Embase, Web of Science and Iranian Database. A meta-analysis was performed using Comprehensive Meta-Analysis Software (BioStat v.2.2). Use of a fixed- or random-effects model was used based on a heterogeneity test, and publication bias was assessed using Begg rank correlation and Egger weighted regression methods.
Results: Of 555 articles published from January 2000 to January 2016, 13 studies were included in this review. The meta-analyses showed that the prevalence of MRSA infection in burn patients was 77.9% (95% confidence interval 70.2-84.0%) among culture-positive cases.
Conclusions: The results of this study indicate that the prevalence of MRSA among burn patients is very high in Iran. Thus, a comprehensive infection control strategy based on hand hygiene, education and training in antibiotic prescribing, environmental cleaning, contact precautions, good antibiotic stewardship and an active surveillance system on the basis of international criteria is urgently needed.
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| http://dx.doi.org/10.1016/j.jgar.2017.10.015 | DOI Listing |
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