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Association between weight-adjusted waist index and obstructive sleep apnea among adults in the United States: data from NHANES (2005-2008 and 2015-2018).
J Int Med Res
January 2025
Quanjiao County People's Hospital, Quanjiao County, Chuzhou, Anhui, China.
Objective: We aimed to examine the relationship between the weight-adjusted waist index (WWI) and obstructive sleep apnea (OSA), a condition often caused by obesity, which remains unclear.
Methods: In this cross-sectional study, we analyzed data from the National Health and Nutrition Examination Survey among adults in the United States (US) aged 20 to 65 years, covering the periods 2005 to 2008 and 2015 to 2018. The study included 8278 participants; we used multivariate logistic regression, restricted cubic splines, and subgroup analyses to explore the relationship between WWI and OSA.
Risk of Motor Vehicle Accidents in Obstructive Sleep Apnea: Comparative Analysis of CPAP Versus Surgery.
Otolaryngol Head Neck Surg
January 2025
Department of Otolaryngology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Objective: To compare the incidence of motor vehicle accidents (MVAs) among patients with obstructive sleep apnea (OSA) undergoing continuous positive airway pressure (CPAP) therapy and sleep surgery.
Study Design: Retrospective cohort study using the TriNetX national clinical database.
Setting: Analysis of a nationwide patient cohort.
[Factors Influencing Obstructive Sleep Apnea Among Employees With Metabolic Syndrome: An Example of a District Hospital in Northern Taiwan].
Hu Li Za Zhi
February 2025
Department of Internal Medicine, Chang Gung Memorial Hospital, Taiwan, ROC.
Background: Obstructive sleep apnea (OSA) is a common sleep disorder shown to be significantly correlated with metabolic syndrome (MS). Healthcare professionals affected by both MS and OSA may suffer from poor sleep quality, raising potential concerns about patient safety. Currently, there remains a gap in research specifically addressing the relationship between MS and OSA in healthcare professionals.
View Article and Find Full Text PDFNight-to-night variability in obstructive sleep apnea: when might a multi-night measurement be helpful?
Expert Rev Respir Med
January 2025
Department of Pulmonology and Sleep Disorders Centre, University Hospital Zurich, Zurich, Switzerland.
Vitronectin regulates lung tissue remodeling and emphysema in chronic obstructive pulmonary disease.
Mol Ther
January 2025
Immune Health, Hunter Medical Research Institute and The University of Newcastle, Newcastle, New South Wales, Australia; Centre for Inflammation, Centenary Institute and University of Technology Sydney, School of Life Sciences, Faculty of Science, Sydney, New South Wales, Australia. Electronic address:
Vitronectin (VTN) is an important extracellular matrix protein in tissue remodeling, but its role in COPD is unknown. We show that VTN regulates tissue remodeling through urokinase plasminogen activator (uPA) signaling pathway in COPD. In human COPD airways and bronchoepithelial cells and the airways of mice with cigarette smoke (CS)-induced experimental COPD, VTN protein was not changed, but downstream uPA signaling was altered (increased plasminogen activator inhibitor-1, uPAR) that induced collagen and airway remodeling.
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