AI Article Synopsis
- * Recent research has identified specific genetic risk factors (alleles) for drug-induced SJS/TEN and shown that screening can help lower its incidence.
- * Despite these advancements, there is still a significant need for further understanding and preventive measures for this serious drug complication.
Article Abstract
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is one of the most devastating of adverse drug reactions (ADRs) and was, until recently, essentially unpredictable. With the discovery of several risk alleles for drug-induced SJS/TEN and the demonstration of effectiveness of screening in reducing incidence, the stage is set for implementation of preventive strategies in populations at risk. Yet much remains to be learned about this potentially fatal complication of commonly used drugs.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805563 | PMC |
| http://dx.doi.org/10.1002/cpt.890 | DOI Listing |
Publication Analysis
Top Keywords
epidermal necrolysis
8
directions genetic
4
genetic predispositions
4
predispositions stevens-johnson
4
stevens-johnson syndrome
4
syndrome toxic
4
toxic epidermal
4
necrolysis stevens-johnson
4
stevens-johnson syndrome/toxic
4
syndrome/toxic epidermal
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!