Cannabinoid hyperemesis syndrome (CHS) is a recently described condition associated with chronic marijuana use. CHS is defined by the triad of chronic marijuana consumption cyclic bouts of nausea and vomiting, plus frequent hot showering. Its etiology, pathogenesis, and epidemiology remain obscure. We interviewed all patients over the age of 18 years attended between February and April 2014 in an outpatient marijuana rehabilitation center. A questionnaire was used to collect sociodemographic and clinical data as well as information related to a diagnosis of CHS. Of 22 patients who met the inclusion criteria, 4 (18.2%) reported symptoms suggestive of CHS; 2 (9.1%) had all symptoms, and 2 (9.1%) had some. CHS is common. We recommend asking about symptoms that might indicate this diagnosis given that CHS generates a high level of discomfort as well as diagnostic errors and many referrals to specialists.
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Clin Toxicol (Phila)
March 2025
School of Medicine, University of Kansas School of Medicine, Kansas City, KS, USA.
Emerg Med J
March 2025
Intensive Care Department, Morriston Hospital, Swansea, UK.
Emerg Med J
March 2025
Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
Ann Emerg Med
February 2025
UCLA Center for Cannabis and Cannabinoids, Jane and Terry Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA.
Cannabinoid hyperemesis syndrome is an underrecognized condition associated with recurrent vomiting and abdominal pain in individuals with prolonged cannabis use. This study used an internet-based survey targeting individuals with self-reported cannabinoid hyperemesis syndrome to assess the burden of disease and to examine associations between heavy cannabis use, early initiation of cannabis use, and cannabinoid hyperemesis syndrome episode frequency. A total of 1,052 participants were included, with the majority reporting frequent cannabis use and significant health care utilization, including emergency department visits and hospitalizations.
View Article and Find Full Text PDFNeurogastroenterol Motil
February 2025
Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, USA.
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