Background: The objective of this study was to determine the cartilage volume and surface area of male and female Beagle dog knees using 3D (3 dimensional) reconstructed MRI images.
Methods: Six Beagle Dogs (Canis familiaris) (3 males and 3 females) of 10-18 months old and weighing between 7.2 and 17.1 kg underwent a MRI evaluation of both knees. The data acquired allowed a 3D reconstruction of the knee and measurement of the cartilage volume and surface area.
Results: Mean knee cartilage volume (averaged over the right and left knees) of animals between 7.2 and 17.1 kg ranged from 319.7 to 647.3 mm; while the mean knee cartilage surface area ranged from 427.14 to 757.2 mm. There was evidence of both knee volume and surface area increasing linearly with animal bodyweight.
Conclusions: The cartilage volume and surface area of the Beagle dog appears to correlate significantly with body weight. This study provides a reference base for future studies investigating cartilage related pathology such as osteoarthritis.
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http://dx.doi.org/10.1186/s40634-017-0109-1 | DOI Listing |
J Magn Reson Imaging
December 2024
Center of Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, USA.
Background: Three-dimensional MR fingerprinting (3D-MRF) has been increasingly used to assess cartilage degeneration, particularly in the knee joint, by looking into multiple relaxation parameters. A comparable 3D-MRF approach can be adapted to assess cartilage degeneration for the hip joint, with changes to accommodate specific challenges of hip joint imaging.
Purpose: To demonstrate the feasibility and repeatability of 3D-MRF in the bilateral hip jointly we map proton density (PD), T, T, T, and ∆B in clinically feasible scan times.
Heliyon
December 2024
Guanghua School of Clinical Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Exosomes have emerged as a crucial focus in advancing the diagnosis and treatment of osteoarthritis (OA). However, there are limited bibliometric studies on this topic. This study aimed to delineate the literature landscape on exosomes in OA, identifying global research trends and key areas.
View Article and Find Full Text PDFSmall
December 2024
Department of Electronic Engineering, Ocean University of China, Qingdao, 266100, China.
Magnetic microrobot swarms have broad application prospects in human-targeted therapy. However, the automated assembly and actuation of functional large-volume swarms is a challenging topic. Chlorella with self-fluorescence and biodegradability is used in this paper as a template to prepare magnetic Chlorella-based microrobots through magnetron sputtering.
View Article and Find Full Text PDFZhongguo Gu Shang
December 2024
Department of Radiology, Sichuan Orthopaedic Hospital, Chengdu 610041, Sichuan, China.
Objective: To explore clinical efficacy of platelet rich plasma (PRP) injection combined with extracorporeal shock wave therapy (ESWT) in treating osteochondral lesion of talus (OLT) with typeⅡa.
Methods: From January 2022 to June 2022, 45 patients with typeⅡa OLT were treated with PRP arthroscopic injection combined with ESWT, including 29 males and 16 females; aged from 18 to 63 years old with an average of(37.7±10.
BMC Musculoskelet Disord
December 2024
Université de Lyon, VetAgro Sup, UPSP ICE 2021.A104, Marcy-l'Etoile, 69280, France.
Objective: This study aimed to assess the effects of an antioxidant-conjugated Hyaluronic Acid (HA), specifically HA-4-aminoresorcinol (HA4AR), on articular cartilage and subchondral bone in osteoarthritis (OA). We conducted a comparative analysis between HA4AR and a commercially available high molecular weight HA formulation in a rabbit model of OA.
Materials And Methods: Eighteen rabbits underwent unilateral anterior cruciate ligament transection (ACLT) and were divided into three groups of six: Saline-group, HA-group, and HA4AR-group, based on the type of intra-articular injection received.
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