A Call to Arms: Quest for a Cryptococcal Vaccine.

Trends Microbiol

Department of Biology, The University of Texas at San Antonio, San Antonio, TX, USA; The South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX, USA. Electronic address:

Published: May 2018

Cryptococcosis remains a significant cause of morbidity and mortality world-wide, particularly among AIDS patients. Yet, to date, there are no licensed vaccines clinically available to treat or prevent cryptococcosis. In this review, we provide a rationale to support continued investment in Cryptococcus vaccine research, potential challenges that must be overcome along the way, and a literature review of the current progress underway towards developing a vaccine to prevent cryptococcosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910246PMC
http://dx.doi.org/10.1016/j.tim.2017.10.002DOI Listing

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