Gabapentin is an anticonvulsant drug widely prescribed for various ailments, including orofacial pain. It was once thought to have no potential for abuse; however, the last decade has seen a dramatic rise in the nonmedical use of gabapentin, particularly among opioid-dependent patients. Gabapentin is sedating and interacts with other sedating medications such as opioids, which can lead to impairment and accidents and may raise the risk of overdose. Dentists must be aware of the potential for abuse of gabapentin and weigh its benefits against its risks when prescribing the drug.
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Stress Health
February 2025
Psychology Department, Mount St. Vincent University, Halifax, Canada.
Adverse childhood experiences (ACEs) have diverse effects on physical development and mental health. This study aimed to clarify the relationship between the quantity of ACE exposure, type of ACE exposure, and subjective level of stress felt, correlated with event-related potential activity across the scalp, while controlling for relevant confounding variables. Fifty-three participants aged 18-32 years completed questionnaires assessing their current mental health, self-regulation, childhood socioeconomic status, and history of traumatic events.
View Article and Find Full Text PDFFront Child Adolesc Psychiatry
July 2024
Counselling Psychology, Faculty of Education, University of Ottawa, Ottawa, ON, Canada.
Introduction: Some targets of relational peer victimization become depressed because of their poor treatment. These associations are well documented in youth but are rarely studied in adults.
Methods: The longitudinal pathways between relational peer victimization (being excluded, stonewalled, etc.
Front Child Adolesc Psychiatry
May 2024
Social Psychiatry and Mental Health, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Introduction: The present study conducted a secondary data analysis of a comprehensive survey from Child Guidance Centers in Japan to identify factors that are associated with child abuse severity in infancy (0-3 years, 1,868 cases) and preschool age (4-6 years, 1,529 cases). A predictive model for abuse severity was developed.
Methods: The data originated from a nationwide survey that was conducted in April 2013, consisting of details of abuse cases, including child characteristics, abuser attributes, and family situation.
Soc Psychol Personal Sci
March 2025
University of Western Ontario, London, Canada.
Intimate partner violence (IPV) is harmful and prevalent, but leaving abusive partners is often challenging due to investments (e.g., children, shared memories).
View Article and Find Full Text PDFJ Extracell Vesicles
January 2025
National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, USA.
The discovery that extracellular RNAs (exRNA) can act as endocrine signalling molecules established a novel paradigm in intercellular communication. ExRNAs can be transported, both locally and systemically in virtually all body fluids. In association with an array of carrier vehicles of varying complexity, exRNA can alter target cell phenotype.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!