AI Article Synopsis
- The study evaluated the repeatability of 18F-FDG PET/MR imaging for measuring glucose uptake in the liver, focusing on standardized uptake values normalized for body weight and lean body mass.
- 35 patients participated in the tests, and various locations in the liver were analyzed for PET/MR accuracy.
- Results showed that the most consistent measurements were taken below the portal vein, indicating it as the best spot for assessing liver glucose uptake.
Article Abstract
Background: To investigate same day 18F-FDG (Fluorodeoxyglucose) PET (Positron Emission Tomography)/MR (Magnetic Resonance) test-retest repeatability of Standardized Uptake Value measurements normalized for body weight (SUV) and lean body mass (SUL) in different locations in the liver.
Methods: This prospective study was IRB approved with written informed consent obtained. 35 patients (20 women and 15 men, 61 ± 11.2 years) that performed a whole-body 18F-FDG PET/MR followed by liver-dedicated contrast-enhanced 18F-FDG PET/MR were included. SUV/L max, mean, and peak were measured inferior to, superior to, and at the right portal vein and in the left lobe of the liver. The coefficient of variation (CV) and intraclass correlation coefficient (ICC) were calculated and Bland-Altman plots were obtained.
Results: The variability for SUV/L's measurements was lowest inferior to the portal vein (<9.2%) followed by measurements performed at the level of the portal vein (<14.6%).
Conclusion: The area inferior to the portal vein is the most reliable location for hepatic 18F-FDG uptake measurements on PET/MR.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612760 | PMC |
| http://dx.doi.org/10.1155/2017/8639731 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!