AI Article Synopsis
- Hypoplasia of the transverse sinus (TS) is a common anatomical variation, and this study investigates its potential link to venous thrombosis, specifically whether it predisposes individuals to ipsilateral thrombosis.
- The researchers analyzed 20 cases with isolated TS thrombosis and compared them to 43 matched controls, using CT and MR venography to diagnose TS conditions and performing statistical analyses.
- Results showed a significant association between TS hypoplasia and thrombosis, indicating that individuals with hypoplastic TS were more likely to experience thrombosis, though this did not affect their functional outcomes after 30 or 90 days.*
Article Abstract
Background: Hypoplasia of the transverse sinus (TS) is a common anatomical variation. However, the relationship between TS hypoplasia and venous thrombosis has not been studied. We analyzed the hypothesis that TS hypoplasia is a predisposing factor for ipsilateral thrombosis.
Materials And Methods: We retrospectively evaluated 20 confirmed cases with isolated TS thrombosis and 43 age- and sex-matched controls. TS thrombosis and hypoplasia were diagnosed using both computed tomography and magnetic resonance venography. Hypoplasia was defined as a TS diameter less than 50% of the cross-sectional diameter of the lumen of the distal superior sagittal sinus and by a bony groove ratio less than 1.02. Univariate analysis was performed to evaluate the association between TS hypoplasia and thrombosis.
Results: There were a total of 45 hypoplastic TS: 31 (49%) left hypoplastic TS (12 (60%) cases vs 19 (44%) controls (P = .24), and 14 (22%) right hypoplastic TS (9 (45%) cases vs 5 (12%) controls (P = .003). TS hypoplasia was more frequently found in cases (n = 18, 90.0%) than in controls (n = 22, 51.2%; relative risk 1.7, confidence interval [CI] 95% 1.3-2.4, P = .003). Hypoplastic TS and ipsilateral TS thrombosis showed a significant association (P = .002 for right and P = .008 for left TS hypoplasia) with relative risk of 3.8 (95% CI 1.3-10) for right and 7.5 (95% CI 1.1-48) for left hypoplasia. No significant association was found between hypoplastic TS and functional outcome at 30- or 90-day follow-up.
Conclusion: TS hypoplasia might be a predisposing factor for ipsilateral TS thrombosis, but not for functional outcome.
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| http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.09.019 | DOI Listing |
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