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Iterative Photoinduced Chain Functionalization as a Generic Platform for Advanced Polymeric Drug Delivery Systems. | LitMetric
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Iterative Photoinduced Chain Functionalization as a Generic Platform for Advanced Polymeric Drug Delivery Systems.

Assala Al Samad Audrey Bethry Olga Janouskova Jérémie Ciccione Christiane Wenk Jean-Luc Coll Gilles Subra Tomas Etrych Fawaz El Omar Youssef Bakkour Jean Coudane Benjamin Nottelet

Macromol Rapid Commun

IBMM (UMR5247), Univ Montpellier, CNRS, ENSCM, Montpellier, France.

Published: February 2018

Advanced drug delivery systems (DDS) are easily designed following a photoiterative strategy. Multifunctional polymers are obtained by coupling building blocks of interest to an alkynated poly(ε-caprolactone) (PCL) platform via an efficient thiol-yne photoaddition. Fine-tuning over the design is achieved, as illustrated with targeting and enzyme-responsive DDS.

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http://dx.doi.org/10.1002/marc.201700502DOI Listing

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