Aim: To identify the potential risk factors of cholangiocarcinoma, we determined the characteristics of cholangiocarcinoma patients among 5 different regions of Thailand.
Methods: All patients diagnosed with cholangiocarcinoma between 2008 and 2013 were identified using the Nationwide Hospital Admission Data registry ( = 39421). Baseline characteristics, comorbidities and survival were abstracted.
Results: The annual incidence during the study period was stable in all regions. Most patients lived in the Northeast (62.8%), followed by the North (16.9%), Central (12.3%), Bangkok (5.4%), and South ( = 2.6%) regions ( < 0.0001). Significantly more cholangiocarcinoma patients had diabetes, cirrhosis, and chronic viral hepatitis B/C infection than non-cholangiocarcinoma participants (diabetes: 11.42% 5.28%; cirrhosis: 4.81% 0.92%; hepatitis B: 0.74% 0.12%; and hepatitis C: 0.50% 0.10%, < 0.0001 for all, respectively). The overall 1-year mortality rate was 81.7%, with a stable trend over time.
Conclusion: Diabetes and chronic liver diseases may be associated with cholangiocarcinoma in the Thai population.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656463 | PMC |
| http://dx.doi.org/10.3748/wjg.v23.i39.7160 | DOI Listing |
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