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Epidemiology of Pediatric Zika Virus Infections. | LitMetric

AI Article Synopsis

  • In July 2016, local transmission of the Zika virus was confirmed in Miami-Dade County, prompting a study on pediatric infections among children aged 1-17.
  • The study analyzed 478 confirmed ZIKV cases, revealing that 33 (6.9%) were in children, primarily travel-associated, with a median age of 11 years and a higher prevalence in Hispanic boys.
  • The majority of symptomatic pediatric cases displayed two of the four main symptoms, and there was a notable link to symptomatic household members during the outbreak.

Article Abstract

Background And Objective: In July 2016, local transmission of Zika virus (ZIKV) was announced in Miami-Dade County, Florida. In this report, we describe the epidemiology of pediatric ZIKV infections in locally acquired and travel-associated cases.

Methods: All children aged 1 to 17 years tested for ZIKV between October 1, 2015, and March 29, 2017, were included. SAS 9.4 was used to analyze age, sex, race and/or ethnicity, origin of exposure, onset date, affiliation with a household cluster, clinical symptoms, hospitalizations, viremia, viruria, and antibody detection in specimens.

Results: Among 478 confirmed ZIKV cases in Miami-Dade County, 33 (6.9%) occurred in children (1-17 years). Twenty-seven (82.3%) cases were travel-associated. The median age of a pediatric Zika case patient was 11 years. Seventeen (51.5%) case patients were boys, and 23 (69.9%) were Hispanic. Among 31 symptomatic cases, all reported having rash, 25 (80.6%) reported fever, 9 (29.0%) reported conjunctivitis, and 7 (22.6%) reported arthralgia. Sixteen (48.5%) cases reported 2 of 4 and 8 (24.2%) reported 3 of 4 main symptoms.

Conclusions: This report found that the majority of children identified during the 2016 ZIKV outbreak only presented with 2 of the 4 main symptoms. In addition, pediatric ZIKV cases were frequently associated with symptomatic household members.

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Source
http://dx.doi.org/10.1542/peds.2017-2044DOI Listing

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