We have studied an X-ray switch based on a gold coated indium antimonide crystal using time-resolved X-ray diffraction and demonstrated that the switch could reduce the pulse duration of a 100 ps X-ray pulse down to 20 ps with a peak reflectivity of 8%. We have used a dynamical diffraction code to predict the performance of the switch, which was then confirmed experimentally. The experiment was carried out at the FemtoMAX beamline at the short-pulse facility of the MAX IV laboratory. The performance and limitation of the switch are discussed in terms of acoustic transport properties between the two materials and the electron transport properties of gold.
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http://dx.doi.org/10.1063/1.4993730 | DOI Listing |
Acta Bioeng Biomech
June 2024
4Department of Pediatric Dentistry and Preclinical Dentistry, Wroclaw Medical University, Wrocław, Poland.
: Caries or iatrogenic thermal trauma of the teeth have a significant impact on the dental pulp structure connected with stimulation of angiogenesis and lymphangiogenesis. Therefore, the aim of the study was to identify the difference in the rate of heat dissipation by vessels present in the dental pulp. : Freshly extracted healthy ( = 10) and carious ( = 14) molars and premolars were cut on a diamond saw and subjected to active thermographic examination and then subjected to lymphoscintigraphy and X-ray examination.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Faculty of Life Sciences, Department of Pharmaceutical Sciences, Laboratory of Macromolecular Cancer Therapeutics (MMCT), University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria.
Splice-switching oligonucleotides (SSOs) can restore protein functionality in pathologies and are promising tools for manipulating the RNA-splicing machinery. Delivery vectors can considerably improve SSO functionality in vivo and allow dose reduction, thereby addressing the challenges of RNA-targeted therapeutics. Here, we report a biocompatible SSO nanocarrier, based on redox-responsive disulfide cross-linked low-molecular-weight linear polyethylenimine (cLPEI), for overcoming multiple biological barriers from subcellular compartments to en-route serum stability and finally in vivo delivery challenges.
View Article and Find Full Text PDFChemistry
January 2025
Institute of Science Tokyo, Department of Chemical Science and Engineering, O-okayama, 152-8552, Meguro-ku, JAPAN.
Switching the location of metal atoms or ions in a molecule has been of great interest as a behavior of molecular machines. We describe herein that the reversible metal translocation can be coupled with the ligand-binding/release of organometallic complexes. The two rhodium moieties sandwiched between arylpolyene ligands exhibit metal-assembly and disassembly through reversible migration between the arene site and the olefin site, in response to the association and dissociation of additional ligands.
View Article and Find Full Text PDFCNS Neurosci Ther
January 2025
Department of Otolaryngology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Background: Sudden sensorineural hearing loss (SSNHL) is associated with abnormal changes in the brain's central nervous system. Previous studies on the brain networks of SSNHL have primarily focused on functional connectivity within the brain. However, in addition to functional connectivity, structural connectivity also plays a crucial role in brain networks.
View Article and Find Full Text PDFMed Phys
January 2025
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Background: The spatial resolution of new, photon counting detector (PCD) CT scanners is limited by the size of the focal spot. Smaller, brighter focal spots would melt the tungsten focal track of a conventional X-ray source.
Purpose: To propose focal spot multiplexing (FSM), an architecture to improve the power of small focal spots and thereby enable higher resolution clinical PCD CT.
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