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http://dx.doi.org/10.21037/tau.2017.03.94 | DOI Listing |
Front Endocrinol (Lausanne)
January 2025
Department of Reproductive Medicine, Nanyang Central Hospital, Nanyang, China.
Objective: Several male factors have been reported to play a role in recurrent pregnancy loss (RPL). The aim of this study is to explore the relationship between semen parameters, sperm DNA fragmentation index (DFI) and RPL.
Method: A total of 1485 participants were recruited from a university hospital between April 2020 and August 2022.
Cryobiology
January 2025
Department of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine, Ataturk University, Erzurum, Turkiye.
Resveratrol is a polyphenol compound showing strong antioxidant properties. It is believed that semen cryopreservation causes significant sperm losses which eventually affects sperm quality. Improving antioxidant status of semen may reduce this damage and enhance sperm fertilizing potential.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Pharmacy, The Second Hospital of Shandong University, 247#, Beiyuan Street, Jinan, 250033, China.
Gastric cancer (GC) is a huge threat to global health, there is no effective treatment or just delay the progression of advanced GC until now. Micro-RNAs were reported to participate in the progression of GC. Clonal formation, MTT, caspase-3 activity, sperm DNA fragmentation, flow cytometry assay, cell adhesion, transwell assays were performed to detect the functions of miR-32-5p or anti-miR-32-5p on the growth and metastasis of GC cells.
View Article and Find Full Text PDFToxicol Appl Pharmacol
January 2025
Department of Medical Biology, Hamidiye School of Medicine, University of Health Sciences, Istanbul, Turkey. Electronic address:
The widespread use of polyethylene terephthalate (PET) in food and beverage packaging raises concerns about its potential health effects, particularly when PET-derived nanoplastics (PET-NPs) are released into the environment. This study investigates the reproductive toxicity of PET-NPs in male mice. Mice were exposed to PET-NPs at doses of 0.
View Article and Find Full Text PDFDNA methylation patterns are inherited from the parental germline to the embryo. In mature sperm, the sites of unmethylated DNA are tightly coupled to sites of histone retention at gene regulatory elements that are implicated in paternal epigenetic inheritance. The timing and mechanism of site-specific DNA demethylation in the male germline currently remains unknown.
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