Purpose: To evaluate the static measurement of the accommodative stimulus-response curve with emoji symbols.
Methods: The accommodative stimulus-response curve was measured in 18 subjects using a Hartmann-Shack sensor to obtain the objective accommodative response from the Zernike defocus term. Measurements were acquired at different accommodative demands, from 0 to 3 D with a step of 0.5 D. Detailed and nondetailed emoji targets were used with two different sizes, corresponding to the two most common visual angles used in smartphones.
Results: A regression analysis was performed to fit the mean results obtained for each target. The determination coefficient was ≥ 0.988 for all targets. For the detailed targets, the slopes for the averaged stimulus-response curve were 0.65 and 0.66 for the bigger and smaller sizes, respectively. For the nondetailed targets, the slopes were 0.60 and 0.58 for the bigger and smaller sizes, respectively. values for these slopes were statistically significant for the two types of targets ( < 0.01).
Conclusions: Our results reveal that the replacement of a word or several words by detailed or nondetailed emoji symbols seems not to provoke a different accommodative response in normal subjects and under standard viewing conditions in the use of smartphones.
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http://dx.doi.org/10.1155/2017/4165706 | DOI Listing |
J Cogn Neurosci
January 2025
Queen's University, Kingston, Ontario, Canada.
Pupil responses are commonly used to provide insight into visual perception, autonomic control, cognition, and various brain disorders. However, making inferences from pupil data can be complicated by nonlinearities in pupil dynamics and variability within and across individuals, which challenge the assumptions of linearity or group-level homogeneity required for common analysis methods. In this study, we evaluated luminance evoked pupil dynamics in young healthy adults (n = 10, M:F = 5:5, ages 19-25 years) by identifying nonlinearities, variability, and conserved relationships across individuals to improve the ability to make inferences from pupil data.
View Article and Find Full Text PDFAm J Physiol Regul Integr Comp Physiol
February 2025
Department of Exercise Sciences, Brigham Young University, Provo, Utah, United States.
The local sweat rate (LSR) response to intradermal electrical stimulation generates a sigmodal stimulus-response curve with a peak sweat rate generated during a 30-s period of continuous stimuli at a frequency of 16-32 Hz. However, the in vivo firing pattern of the sudomotor nerve resembles more of a bursting pattern. We tested the hypothesis that a bursting pattern during intradermal electrical stimulation would result in a greater sweating response than the regular continuous stimulus pattern.
View Article and Find Full Text PDFJ Biol Chem
November 2024
Laboratory of Biocomplexity and Engineering Biology, School of Medicine, The Chinese University of Hong Kong, Shenzhen, China; Futian Biomedical Innovation R&D Center, The Chinese University of Hong Kong, Shenzhen, China; Ciechanover Institute of Precision and Regenerative Medicine, School of Medicine, The Chinese University of Hong Kong, Shenzhen, China; Center for Endocrinology and Metabolic Diseases, Second Affiliated Hospital, The Chinese University of Hong Kong, Shenzhen, China. Electronic address:
The stimulus-response curve is usually modeled by the Hill function due to its simplicity and clear molecular mechanisms (Michaelis-Menten type of kinetics). Unfortunately, the mechanisms do not explain why the stimulus is ubiquitously measured by logarithmic dose rather than the dose itself and why the log(dose)-response curve possesses such fine properties as symmetry and wide adjustability. Here, the dose-response is considered from a holistic perspective spanning multiple biological levels from molecules to the whole organism, which reveals that an appropriate model for log(dose) response is the cumulative normal distribution (CND) function, which had only statistical implication previously but now possess mechanistic-statistical duality.
View Article and Find Full Text PDFEur J Neurosci
December 2024
Department of Neuromuscular Physiotherapy, Poznan University of Physical Education, Poznan, Poland.
The aim of the present study was to determine if anodal transcutaneous spinal direct current stimulation (tsDCS) affects corticospinal excitability (CSE) and voluntary activation (VA) of the quadriceps femoris muscle (QM). This was a double-blind, randomized study in which spine-shoulder anodal tsDCS (active electrode centered over T11-12, 2.5 mA, 20 min) was applied in a seated position.
View Article and Find Full Text PDFNeurorehabil Neural Repair
January 2025
Department of Neurology, Emory University, School of Medicine, Atlanta, GA, USA.
Background: Low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) protocols targeting primary motor cortex (M1) are used in rehabilitation of neurological diseases for their therapeutic potential, safety, and tolerability. Although lower intensity LF-rTMS can modulate M1 neurophysiology, results are variable, and a systematic assessment of its dose effect is lacking.
Objectives: To determine the dose-response of LF-rTMS on stimulated and non-stimulated M1.
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